The first edition of __Forensic DNA Typing,__ published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, __Advanced Topics in Forensic DNA Typing: Interpretation__. This book builds upon the previous two editions of __Forensic DNA Typing__ books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling __Advanced Topics in Forensic DNA Typing: Methodology__, published in September 2011. * Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence * Worked mixture examples illustrate the impact of different statistical approaches for reporting results * Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011 Content: About this Book, Page ii Front Matter, Page iii Copyright, Page iv Dedication, Page v Foreword, Pages ix-x Introduction, Pages xi-xvi Acknowledgments, Page xvii About the Author, Pages xix-xx Chapter 1 - Data Interpretation Overview, Pages 3-24 Chapter 2 - Data, Models, Thresholds, Pages 25-46 Chapter 3 - STR Alleles and Amplification Artifacts, Pages 47-86 Chapter 4 - STR Genotypes: Heterozygote Balance, Stochastic Thresholds, Allele, and Concordance Studies, Pages 87-108 Chapter 5 - STR Profiles: Multiplex PCR, Tri-Alleles, Amelogenin, and Partial Profiles, Pages 109-127 Chapter 6 - DNA Mixtures, Pages 129-158 Chapter 7 - Low-Level DNA and Complex Mixtures, Pages 159-182 Chapter 8 - Troubleshooting Data Collection, Pages 183-210 Chapter 9 - Statistical Interpretation Overview, Pages 213-237 Chapter 10 - STR Population Data Analysis, Pages 239-279 Chapter 11 - DNA Profile Frequency Estimates and Match Probabilities, Pages 281-308 Chapter 12 - DNA Mixture Statistics, Pages 309-332 Chapter 13 - Coping with Potential Missing Alleles, Pages 333-348 Chapter 14 - Relationship Testing: Kinship Statistics, Pages 349-401 Chapter 15 - Lineage Marker Statistics, Pages 403-444 Chapter 16 - Laboratory Reports: Communicating Results and Conclusions, Pages 445-495 Appendix 1 - STR Allele Frequencies from U.S. Population Data, Pages 497-518 Appendix 2 - NRC I & NRC II Recommendations, Pages 519-528 Appendix 3 - DAB Recommendations on Statistics, Pages 529-536 Appendix 4 - Worked Mixture Example, Pages 537-567 Index, Pages 569-585
The first edition of Forensic DNA Typing, published in 2001, by John Butler quickly established itself as the gold-standard reference for the field. Over the next ten years, the vast amount of new information uncovered has resulted in this new volume, Advanced Topics in Forensic DNA Typing: Interpretation. This book builds upon the previous two editions of Forensic DNA Typing books, but with a focus on mixture interpretation and statistical analysis and is a companion to the bestselling Advanced Topics in Forensic DNA Typing: Methodology, published in September 2011.
- Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence
- Worked mixture examples illustrate the impact of different statistical approaches for reporting results
- Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011
Advanced Topics in Forensic DNA Typing: Interpretation builds upon the previous two editions of John Butler{u2019}s internationally acclaimed Forensic DNA Typing textbook with forensic DNA analysts as its primary audience. Intended as a third-edition companion to the Fundamentals of Forensic DNA Typing volume published in 2010 and Advanced Topics in Forensic DNA Typing: Methodology published in 2012, this book contains 16 chapters with 4 appendices providing up-to-date coverage of essential topics in this important field. Over 80 % of the content of this book is new compared to previous editions. Provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence Worked mixture examples illustrate the impact of different statistical approaches for reporting results Includes allele frequencies for 24 commonly used autosomal STR loci, the revised Quality Assurance Standards which went into effect September 2011 Annotation This title provides forensic DNA analysts coverage of the crucial topic of DNA mixture interpretation and statistical analysis of DNA evidence. Worked mixture examples illustrate the impact of different statistical approaches for reporting results. It includes allele frequencies for 24 commonly used autosomal STR loci
