## Preface to Volume 1 Preface to Volume 10 This is the tenth volume of Advances in Human Genetics and some fifty different reviews covering a very wide range of topics have now appeared. Many of the earlier articles still stand as valuable sources of reference. But the subject continues to move forward at an increasing speed and its vitality is indicated by its remarkable recruitment of young investigators. New areas of research which could hardly have been envisaged only a few years ago have emerged, and quite unexpectedly discoveries have been made in parts of the subject which only recently had come to be thought as fully explored. So there continues to be a need for authoritative and critical reviews intended to keep workers in the various branches of this seemingly ever-expanding subject fully informed about the progress that is being made and also, of course, to provide a ready and accessible account of new developments in human genetics for those whose primary interests are in other fields of biological and medical research. We see no reason to alter the general policy which was outlined in the preface to the first volume. We believe that it has served our readers well. The subject seems to us to be just as exciting and intellectually stimulating and rewarding as it did when this series was first started. We expect the next decade of research in human genetics to be as innovative and productive as the last and our aim is to record its progress in Advances in Human Genetics. Front Matter....Pages i-xix The Lethal Osteochondrodysplasias....Pages 1-103 Mutations in Type I Procollagen Genes That Cause Osteogenesis Imperfecta....Pages 105-132 Structural Defects in Inherited and Giant Platelet Disorders....Pages 133-234 Genetic Aspects of Immunoglobulin A Deficiency....Pages 235-266 Oxidative Phosphorylation Diseases....Pages 267-330 Addendum....Pages 331-332 Back Matter....Pages 333-339 From reviews of previous volumes in the series: 'Extremely valuable ... thoroughly recommended.'-Annals of Human Genetics 'The most lucid and stimulating discussions of the topic to be found anywhere.'-American Scientist