This first book to focus on all principles and aspects of AFM in liquid phase is perfectly structured, making it easy-to-follow for non-AFM specialists. At the same time, it is an excellent introduction for researchers wishing to use this important technique for evaluating biological material and biological applications. From the contents: * AFM: Basic concept * Dynamic modes in liquids * Force spectroscopy * Forces in liquids * Single molecule force spectroscopy * High resolution imaging of biological material * Imaging of force-distance curves * High speed AFM for observing dynamic processes * Theory and fundamentals * Combination of AFM with optical methods * Biological applications * Electrochemical AFM * Manipulation and lithography An optimum balance for chemists, physicists, materials scientists, and biologists, as well as analytical and medicinal chemists. Content: Chapter 1 AFM: Basic Concepts (pages 1–34): Fernando Moreno?Herrero and Julio Gomez?Herrero Chapter 2 Carbon Nanotube Tips in Atomic Force Microscopy with Applications to Imaging in Liquid (pages 35–64): Edward D. de Asis, Joseph Leung and Cattien V. Nguyen Chapter 3 Force Spectroscopy (pages 65–86): Prof. Arturo M. Baro Chapter 4 Dynamic?Mode AFM in Liquid (pages 87–119): Takeshi Fukuma and Michael J. Higgins Chapter 5 Fundamentals of AFM Cantilever Dynamics in Liquid Environments (pages 121–155): Daniel Kiracofe, John Melcher and Arvind Raman Chapter 6 Single?Molecule Force Spectroscopy (pages 157–187): Albert Galera?Prat, Rodolfo Hermans, Ruben Hervas, Angel Gomez?Sicilia and Mariano Carrion?Vazquez Chapter 7 High?Speed AFM for Observing Dynamic Processes in Liquid (pages 189–209): Toshio Ando, Takayuki Uchihashi, Noriyuki Kodera, Mikihiro Shibata, Daisuke Yamamoto and Hayato Yamashita Chapter 8 Integration of AFM with Optical Microscopy Techniques (pages 211–229): Zhe Sun, Andreea Trache, Kenith Meissner and Gerald A. Meininger Chapter 9 AFM Imaging in Liquid of DNA and Protein–DNA Complexes (pages 231–258): Yuri L. Lyubchenko Chapter 10 Stability of Lipid Bilayers as Model Membranes: Atomic Force Microscopy and Spectroscopy Approach (pages 259–284): Lorena Redondo?Morata, Marina Ines Giannotti and Fausto Sanz Chapter 11 Single?Molecule Atomic Force Microscopy of Cellular Sensors (pages 285–306): Jurgen J. Heinisch and Yves F. Dufrene Chapter 12 AFM?Based Single?Cell Force Spectroscopy (pages 307–330): Clemens M. Franz and Anna Taubenberger Chapter 13 Nanosurgical Manipulation of Living Cells with the AFM (pages 331–354): Atsushi Ikai, Rehana Afrin, Takahiro Watanabe?Nakayama and Shin?Ichi Machida This first book to focus on this important technique is perfectly structured, making it easy-to-follow for non-AFM specialists, while equally providing an excellent introduction for researchers wishing to use AFM for evaluating biological material and biological applications.