InTeOp – 2012, 335 pages ISBN: 9535108788, 9789535108788 The book introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here. This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis. Contents: Preface Section 1 Analysis of Biological Networks Hierarchical Biological Pathway Data Integration and Mining Investigation on Nuclear Transport of Trypanosoma brucei: An in silico Approach Systemic Approach to the Genome Integration Process of Human Lentivirus Section 2 Sequence Analysis SeqAnt 2012: Recent Developments in Next-Generation Sequencing Annotation Section 3 High-Performance Computing Towards a Hybrid Federated Cloud Platform to Efficiently Execute BioinformaticsWorkflows Hardware Accelerated Molecular Docking: A Survey Section 4 Molecular Modeling Incorporating Molecular Dynamics Simulations into Rational Drug Design: A Case Study on Influenza a Neuraminidases Using Molecular Modelling to Study Interactions Between Molecules with Biological Activity Section 5 Structural Bioinformatics On the Assessment of Structural Protein Models with ROSETTA-Design and HMMer: Value, Potential and Limitations Section 6 Intelligent Data Analysis Bacterial Promoter Features Description and Their Application on E. coli in silico Prediction and Recognition Approaches Computational Approaches for Designing Efficient and Specific siRNAs Novel microRNA Cloning Using Bioinformatics Ensemble Clustering for Biological Datasets Research on Pattern Matching with Wildcards and Length Constraints: Methods and Completeness This book is divided into different research areas relevant in Bioinformatics such as biological networks, next generation sequencing, high performance computing, molecular modeling, structural bioinformatics, molecular modeling and intelligent data analysis. Each book section introduces the basic concepts and then explains its application to problems of great relevance, so both novice and expert readers can benefit from the information and research works presented here
