Biomacromolecules : introduction to structure, function, and informatics

This book provides an integrated treatment of the structure and function of nucleic acids, proteins, and glycans, including thorough coverage of relevant computational biochemistry. The text begins with an introduction to the biomacromolecules, followed by discussion of methods of isolation and purification, physiochemical and biochemical properties, and structural characteristics. The next section of the book deals with sequence analysis, analysis of conformation using spectroscopy, chemical synthesis, and computational approaches. The following chapters discuss biomolecular interactions, enzyme action, gene transmission, signal transduction, and biomacromolecular informatics. The author concludes with presenting the latest findings in genomics, proteomics, glycomics, and biomacromolecular evolution. This text is an invaluable resource for research professionals wishing to move into genomics, proteomics, and glycomics research. It is also useful for students in biochemistry, molecular biology, bioengineering, biotechnology, and bioinformatics. Provides An Integrated Presentation Of The Structure And Function Of Nucleic Acids, Proteins, And Glycans, Including The Latest Findings From The Fields Of Genomics, Proteomics, And Glycomics. It Serves As A Bridge Between Introductory Biochemistry Textbooks And Advanced Treatises On Individual Classes Of Biomacromolecules. The Integrated Treatment Of Biomacromolecules Enables The Reader To Gain A Better Understanding And Appreciation Of Both The Similarities And Differences Among The Three Classes Of Biomacromolecules Examined In The Text. Introduction -- Monomer Constituents Of Biomacromolecules -- Purification And Characterization -- Biomacromolecular Structure: Nucleic Acids -- Biomacromolecular Structure: Proteins -- Biomacromolecular Structure: Polysaccharides -- Studies Of Biomacromolecular Structures: Spectroscopic Analysis Of Conformation -- Studies Of Biomacromolecular Structures: Chemical Synthesis -- Studies Of Biomacromolecular Structures: Computation And Modeling -- Biomacromolecular Interaction -- Biomacromolecular Catalysis -- Signal Transduction And Biodegradation -- Biosynthesis And Genetic Transmission -- Biomacromolecular Informatics -- Proteomics -- Glycomics -- Biomacromolecular Evolution. C. Stan Tsai. Includes Bibliographical References And Index. This book is the first to offer an integrated, comprehensive overview of the structure and function of biomacromolecules together with a summary of the latest advances from bioinformatics and functional genomics.