Biomedical Informatics (Methods in Molecular Biology (569))

In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In __Biomedical Informatics__, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful __Methods in Molecular BiologyTM__ series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Wide-ranging and innovative, __Biomedical Informatics__ is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers. In Recent Decades, Bioinformatics Has Emerged As A Dynamic Area Producing A Wide Spectrum Of New Approaches And Playing An Important Role In Modern Biotechnological Development. This Book Provides An Overview Of Novel Cyberinfrastructures Which Are Currently Under Development In Various Biomedical Centers Around The World. The First Three Chapters Demonstrate Various Architectures For Large-scale Collaboration Which Integrate Scientific Accord Across Multiple Centers. The Next Five Chapters Demonstrate Modern Approaches Currently Used In Various Areas Of Bioinformatics. The Final Four Chapters Illustrate The Software Challenges And Strategies To Resolve Those Challenges For Large-scale Biomedical Informatics Projects--page V. 1. Management Of Information In Distributed Biomedical Collaboratories / David B. Keator -- 2. Enabling Public Data Sharing: Encouraging Scientific Discovery And Education / Christine Fennema-notestine -- 3. Mediator Infrastructure For Information Integration And Semantic Data Integration Environment For Biomedical Research / Jeffrey S. Grethe, Edward Ross, David Little, Brian Sanders, Amarnath Gupta, And Vadim Astakhov -- 4. System Biology Of Gene Regulation / Michael Baitaluk -- 5. Current Computational Methods For Prioritizing Candidate Regulatory Polymorphisms / Stephen Montgomery -- 6. Methods Of Information Geometry In Computational System Biology (consistency Between Chemical And Biological Evolution) / Vadim Astakhov -- 7. Protein Structure Prediction Based On Sequence Similarity / Lukasz Jaroszewsky -- 8. Applications Of Bioinformatics To Protein Structures: How Protein Structure And Bioinformatics Overlap / Gye Won Han, Chris Rife, And Michael R. Sawaya -- 9. Knowledge Discovery Via Machine Learning For Neurodegenerative Disease Researchers / I. Burak Özyurt And Gregory G. Brown -- 10. Brain Model Of Text Animation As A Data Mining Strategy / Tamara Astakhova And Vadim Astakhov -- 11. Processes Parallel Execution Using Grid Wizard Enterprise / Marco Ruiz -- 12. Single Sign-on In A Grid Portal / Ramil V. Manansala. Edited By Vadim Astakhov. Includes Bibliographical References And Index.

In past decades, the area of bioinformatics has proved to be both dynamic and vital, producing a wide spectrum of novel approaches and assuming an increasingly important role in modern bio-technological development. In Biomedical Informatics, expert researchers explore cutting-edge new advances in the field, providing an overview of novel cyberinfrastructures which are currently under development in various bio-medical centers across the world. Chapters demonstrate various architectures for large-scale collaboration, offer modern approaches currently used in various areas of bioinformatics, and highlight the software challenges associated with large-scale biomedical informatics. Composed in the highly successful Methods in Molecular BiologyTM series format, chapters include a brief introduction, detailed methods, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls.

Wide-ranging and innovative, Biomedical Informatics is an essential manual for newcomers to this area, as well as an invaluable addition to the laboratories and offices of the most practiced researchers.

Front Matter....Pages ii-ix Back Matter....Pages 1-23 ....Pages 25-32