This volume is based on the Symposium on "The Brain and Human Behavior," held in October of 1969 as a part of the centennial observance of the Loyola Uni versity of Chicago. As President of the University, I was pleased to offer the University's support for the organization of this Symposium and to participate in some of its sessions. The volume which I now have the pleasure to introduce employs the materials of the Symposium as a framework. Its chapters constitute updated and greatly expanded versions of the original presentations, edited and organized so as to constitute an integrated picture of Neurosciences and their epistemological aspects. It seems appropriate for me to describe at this time certain features of this Jesuit University and of its Centennial which are particularly pertinent in the context of the present volume. Loyola University of Chicago opened its classes on September 5, 1870 with a faculty of 4 and a student body of 37. Today, Loyola University is the largest in dependent University in Illinois and the largest institution of higher learning under Catholic sponsorship in the United States of America. The University comprises twelve schools and colleges, a faculty of more than 1,600 and a student body of 16,545. As an institution of learning, this University is dedicated to knowledge; but perhaps more particularly than others, it is dedicated to the integration of truth and the knowledge of man as such. Front Matter....Pages I-XI Introduction....Pages 1-20 Front Matter....Pages 21-21 Molecular Organization of Synapses for Chemical Transmission in the Central Nervous System....Pages 22-35 Discussion of De Robertis’ Paper....Pages 35-37 Possible Synaptic Mechanism Subserving Learning....Pages 39-61 Synaptic Modulations....Pages 63-92 Front Matter....Pages 93-93 Some Brain Protein Changes Reflecting Neuronal Plasticity at Learning....Pages 94-110 Discussion on Hydén’s Paper....Pages 110-114 Norepinephrine in the Central Nervous System and its Correlations with Behavior....Pages 115-128 Discussion of Kety’s Paper....Pages 128-129 Some Monoaminergic Mechanisms Controlling Sleep and Waking....Pages 131-161 Discussion of Jouvet’s Paper....Pages 161-162 Front Matter....Pages 163-163 Data Structure and Algorithms in the Primate Somatosensory Cortex....Pages 164-186 Cortical Visual Areas and Their Interactions....Pages 187-208 Neurophysiological and Psychophysical Correlates in Vision Research....Pages 209-258 Integrative Properties of Parastriate Neurons....Pages 259-289 Neural Correlates of Learning and Memory....Pages 291-301 Electrophysiological Correlates of Positive Reinforcement: Post-Reinforcement Synchronization, Modulation of Sensory Input, and Steady Potentials....Pages 303-321 Front Matter....Pages 323-323 Nature, Nurture and the Psychological Approach to Learning....Pages 324-340 Phylogeny of Memory Development in Vertebrates....Pages 341-349 Discussion of Beritashvili’s Paper....Pages 350-351 Front Matter....Pages 323-323 Time, Space, Motivation, Memory and Decision....Pages 353-376 The Ontogeny of Behavior and the Concept of Instinct....Pages 377-392 Operational Structures of the Intelligence and Organic Controls....Pages 393-398 Front Matter....Pages 399-399 In Defense of Teleology....Pages 400-408 The Mentality of Man’s Brain....Pages 409-422 What Difference Does Mind Make?....Pages 423-447 Conditions for a Mechanistic Theory for Behaviour....Pages 449-465 Back Matter....Pages 467-475