Calcium Signaling

This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com. Front Matter ....Pages i-xiii Calcium Signaling: From Basic to Bedside (Md. Shahidul Islam)....Pages 1-6 Measuring Ca2+ in Living Cells (Joseph Bruton, Arthur J. Cheng, Håkan Westerblad)....Pages 7-26 High-Throughput Fluorescence Assays for Ion Channels and GPCRs (Irina Vetter, David Carter, John Bassett, Jennifer R. Deuis, Bryan Tay, Sina Jami et al.)....Pages 27-72 Imaging Native Calcium Currents in Brain Slices (Karima Ait Ouares, Nadia Jaafari, Nicola Kuczewski, Marco Canepari)....Pages 73-91 Molecular Diversity of Plasma Membrane Ca2+ Transporting ATPases: Their Function Under Normal and Pathological Conditions (Luca Hegedűs, Boglárka Zámbó, Katalin Pászty, Rita Padányi, Karolina Varga, John T. Penniston et al.)....Pages 93-129 A Role for SERCA Pumps in the Neurobiology of Neuropsychiatric and Neurodegenerative Disorders (Aikaterini Britzolaki, Joseph Saurine, Benjamin Klocke, Pothitos M. Pitychoutis)....Pages 131-161 Cytoplasmic Calcium Buffering: An Integrative Crosstalk (Juan A. Gilabert)....Pages 163-182 An Update to Calcium Binding Proteins (Jacobo Elíes, Matilde Yáñez, Thiago M. C. Pereira, José Gil-Longo, David A. MacDougall, Manuel Campos-Toimil)....Pages 183-213 Phospholipase C (Colin A. Bill, Charlotte M. Vines)....Pages 215-242 New Insights in the IP3 Receptor and Its Regulation (Jan B. Parys, Tim Vervliet)....Pages 243-270 Expression of the Inositol 1,4,5-Trisphosphate Receptor and the Ryanodine Receptor Ca2+-Release Channels in the Beta-Cells and Alpha-Cells of the Human Islets of Langerhans (Fabian Nordenskjöld, Björn Andersson, Md. Shahidul Islam)....Pages 271-279 Evolution of Excitation-Contraction Coupling (John James Mackrill, Holly Alice Shiels)....Pages 281-320 Molecular Insights into Calcium Dependent Regulation of Ryanodine Receptor Calcium Release Channels (Naohiro Yamaguchi)....Pages 321-336 Sarco-Endoplasmic Reticulum Calcium Release Model Based on Changes in the Luminal Calcium Content (Agustín Guerrero-Hernández, Víctor Hugo Sánchez-Vázquez, Ericka Martínez-Martínez, Lizeth Sandoval-Vázquez, Norma C. Perez-Rosas, Rodrigo Lopez-Farias et al.)....Pages 337-370 Pyridine Nucleotide Metabolites and Calcium Release from Intracellular Stores (Antony Galione, Kai-Ting Chuang)....Pages 371-394 Calcium Signaling in the Heart (Derek A. Terrar)....Pages 395-443 Molecular Basis and Regulation of Store-Operated Calcium Entry (Jose J. Lopez, Isaac Jardin, Letizia Albarrán, Jose Sanchez-Collado, Carlos Cantonero, Gines M. Salido et al.)....Pages 445-469 Canonical Transient Potential Receptor-3 Channels in Normal and Diseased Airway Smooth Muscle Cells (Yong-Xiao Wang, Lan Wang, Yun-Min Zheng)....Pages 471-487 Pathophysiological Significance of Store-Operated Calcium Entry in Cardiovascular and Skeletal Muscle Disorders and Angiogenesis (Javier Avila-Medina, Isabel Mayoral-González, Isabel Galeano-Otero, Pedro C. Redondo, Juan A. Rosado, Tarik Smani)....Pages 489-504 Calcium Signaling and the Regulation of Chemosensitivity in Cancer Cells: Role of the Transient Receptor Potential Channels (Giorgio Santoni, Maria Beatrice Morelli, Oliviero Marinelli, Massimo Nabissi, Matteo Santoni, Consuelo Amantini)....Pages 505-517 Widespread Roles of CaMK-II in Developmental Pathways (Sarah C. Rothschild, Robert M. Tombes)....Pages 519-535 Calcium Signaling and Gene Expression (Basant K. Puri)....Pages 537-545 Review: Structure and Activation Mechanisms of CRAC Channels (Carmen Butorac, Adéla Krizova, Isabella Derler)....Pages 547-604 Targeting Transient Receptor Potential Channels by MicroRNAs Drives Tumor Development and Progression (Giorgio Santoni, Maria Beatrice Morelli, Matteo Santoni, Massimo Nabissi, Oliviero Marinelli, Consuelo Amantini)....Pages 605-623 Calcium Channels and Calcium-Regulated Channels in Human Red Blood Cells (Lars Kaestner, Anna Bogdanova, Stephane Egee)....Pages 625-648 Regulation of Multifunctional Calcium/Calmodulin Stimulated Protein Kinases by Molecular Targeting (Kathryn Anne Skelding, John A. P. Rostas)....Pages 649-679 Readily Releasable Stores of Calcium in Neuronal Endolysosomes: Physiological and Pathophysiological Relevance (Koffi L. Lakpa, Peter W. Halcrow, Xuesong Chen, Jonathan D. Geiger)....Pages 681-697 At the Crossing of ER Stress and MAMs: A Key Role of Sigma-1 Receptor? (Benjamin Delprat, Lucie Crouzier, Tsung-Ping Su, Tangui Maurice)....Pages 699-718 ER-Mitochondria Calcium Transfer, Organelle Contacts and Neurodegenerative Diseases (Francesca Vallese, Lucia Barazzuol, Lorenzo Maso, Marisa Brini, Tito Calì)....Pages 719-746 The Role of Mitochondrial Calcium Signaling in the Pathophysiology of Cancer Cells (Andra M. Sterea, Yassine El Hiani)....Pages 747-770 Simulation Strategies for Calcium Microdomains and Calcium Noise (Nicolas Wieder, Rainer H. A. Fink, Frederic von Wegner)....Pages 771-797 A Statistical View on Calcium Oscillations (Jake Powell, Martin Falcke, Alexander Skupin, Tomas C. Bellamy, Theodore Kypraios, Rüdiger Thul)....Pages 799-826 Calcium Regulation of Bacterial Virulence (Michelle M. King, Biraj B. Kayastha, Michael J. Franklin, Marianna A. Patrauchan)....Pages 827-855 Ca2+ Signaling in Drosophila Photoreceptor Cells (Olaf Voolstra, Armin Huber)....Pages 857-879 Calcium Imaging in Drosophila melanogaster (Nicola Vajente, Rosa Norante, Paola Pizzo, Diana Pendin)....Pages 881-900 Calcium Imaging in the Zebrafish (Petronella Kettunen)....Pages 901-942 Stimulus-Secretion Coupling in Beta-Cells: From Basic to Bedside (Md. Shahidul Islam)....Pages 943-963 Calcium Dynamics and Synaptic Plasticity (Pedro Mateos-Aparicio, Antonio Rodríguez-Moreno)....Pages 965-984 Calcium Signaling During Brain Aging and Its Influence on the Hippocampal Synaptic Plasticity (Ashok Kumar)....Pages 985-1012 Calcium Signaling in Endothelial Colony Forming Cells in Health and Disease (Francesco Moccia)....Pages 1013-1030 Sensing Extracellular Calcium – An Insight into the Structure and Function of the Calcium-Sensing Receptor (CaSR) (Sergei Chavez-Abiega, Iris Mos, Patricia P. Centeno, Taha Elajnaf, Wolfgang Schlattl, Donald T. Ward et al.)....Pages 1031-1063 Extracellular Ca2+ in Bone Marrow (Ryota Hashimoto)....Pages 1065-1078 Calcium in Cell-Extracellular Matrix Interactions (Sandeep Gopal, Hinke A. B. Multhaupt, John R. Couchman)....Pages 1079-1102 Back Matter ....Pages 1103-1110 "This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish"--Publisher's description