Cardiovascular and Musculoskeletal Systems

This volume is one of a set of concise, well illustrated and authoritative studies of natural and experimental lesions of laboratory animals (rat, mouse and hamster) arranged by organ systems. Precise differential diagnostic criteria and terminology are given emphasis. Included are useful data on pathogenesis, etiology, biologic behavior, frequency in different strains and under varying laboratory conditions. Front Matter....Pages I-XVII Front Matter....Pages 1-1 Nutritional Cardiomyopathy: Selenium-Vitamin E Deficiency, Mouse and Rat....Pages 3-9 Inherited Dystrophic Cardiac Calcinosis, Mouse....Pages 9-14 Calcification of the Heart, Hamster....Pages 15-17 Hereditary Cardiomyopathy, Syrian Hamster....Pages 18-22 Cardiotoxicity of Ionophores, Rat....Pages 23-29 Myocardial Disease Associated with the Feeding of Unsaturated Vegetable Oil, Rat....Pages 29-37 Atrial Thrombosis, Rat, Mouse, and Hamster....Pages 37-41 Left Ventricular Hypertrophy....Pages 41-50 Encephalitozoonosis of the Cardiovascular System, Rat and Mouse....Pages 50-52 Myocarditis Due to Coxsackievirus B3, Mouse....Pages 53-55 Endocardial Sarcoma, Rat....Pages 56-62 Endomyocardial Neurofibromatosis, Rat....Pages 62-68 Polyarteritis, Rat....Pages 71-76 Drug-Induced Lesions, Arteries, Rat....Pages 76-83 Drug-Induced Lesions of the Coronary Artery, Dog....Pages 84-90 Angiosarcoma of the Renal Capsule, Mouse....Pages 91-97 Front Matter....Pages 99-99 Procedures for Morphologic Studies of Skeletal Muscle, Rat, Mouse, and Hamster....Pages 101-108 Pathologic Reactions of Skeletal Muscle to Injury....Pages 109-126 Rhabdomyosarcoma of the Subcutis, Rat....Pages 127-135 Rhabdomyosarcoma, Mouse and Hamster....Pages 135-140 Front Matter....Pages 99-99 Congenital Osteopetrosis, Mouse....Pages 237-246 Congenital Osteopetrosis, Rat....Pages 246-252 Hereditary Progressive Ankylosis, Mouse....Pages 252-257 Bone Lesions, X-Linked Hypophosphatemic ( Hyp ) Mouse....Pages 257-262 X Chromosome-Linked Muscular Dystrophy (mdx) of the Skeletal Muscle, Mouse....Pages 149-155 Dystonia Musculorum Deformans, Sprague-Dawley Rat with the Dystonic (dt) Mutation....Pages 155-156 Motor End-Plate Disease, Mouse....Pages 156-159 Jolting Mouse....Pages 160-164 Osteoma, Spontaneous and Virus-Induced, Mouse....Pages 182-190 Osteosarcoma of the Bone Experimentally Induced by Moloney Sarcoma Virus, Rat....Pages 190-198 Osteosarcoma, Spontaneous and Chemically Induced, Rat....Pages 199-201 Osteosarcoma, Spontanous and Radiation-Induced, Mouse....Pages 202-213 Chordoma, Rat....Pages 214-218 Ameloblastic Odontoma of the Mandible, Rat....Pages 218-224 Osteofibroma, Mouse....Pages 224-228 Ossifying Fibroma, Mouse....Pages 228-232 Malignant Fibrous Histiocytoma of the Soft Tissue and Bone, Rat....Pages 233-236 Sarcocystosis of the Skeletal and Cardiac Muscle, Mouse....Pages 165-169 Development of the Skeleton, Rat....Pages 173-181 Nutritional Myopathy: Selenium-Vitamin E Deficiency, Rat and Mouse....Pages 141-148 Front Matter....Pages 99-99 Hormonal Effects on Bone, Rat....Pages 263-273 Lathyrogen-Induced Lesions of Bone, Rat....Pages 273-279 Chondro-Osseous Lesions Induced by Adriamycin, Rabbit....Pages 279-284 Osteopetrosis Induced by Retrovirus, Mouse....Pages 284-291 Osteochondrosis, Rat....Pages 291-296 Back Matter....Pages 297-312 This is the ninth volume in a series dealing with induced lesions in laboratory animals. The information on pathology and toxicology documented in the series is an aid to scientific institutions, industry and government agencies charged with the safety testing of food, drugs and chemicals.