LEARN NEUROSCIENCE IN THE CONTEXT OF REAL-LIFE PATIENTS AND PREPARE FOR THE BOARDS Experience with clinical cases is key to excelling on the USMLE Step 1 and shelf exams, and ultimately to providing patients with competent clinical care. __Case Files: Neuroscience__ provides 49 true-to-life cases that illustrate essential concepts in this field. Each case includes an easy-tounderstand discussion correlated to essential basic science concepts, definitions of key terms, neuroscience pearls, and USMLE-style review questions. With Case Files, you'll learn instead of memorize. * Learn from 49 high-yield cases, each with board-style questions and key-point pearls * Master complex concepts through clear and concise discussions * Practice with review questions to reinforce learning * Polish your approach to clinical problem-solving * Perfect for medical, physical therapy, and neuroscience students preparing for course exams and the Boards Cover 1 Copyright Page 3 Contents 6 Preface 12 Section I: Approach to Learning Neurosciences 16 Part 1. The Big Picture 17 Part 2. Know the Tracts 17 Part 3. Understand the Terminology 18 Section II: Clinical Cases 20 Forty-Nine Case Scenarios 22 Cell Types of the Nervous System 22 The Neuron 30 Electrical Properties of Nerves and Resting Membrane Potential 38 The Myelin Sheath and Action Potentials 46 Neural Synapses 56 Synaptic Integration 64 Neurotransmitter Types 72 Neurotransmitter Release 80 Neurotransmitter Receptors 88 The Neuromuscular Junction 96 Central Nervous System Development 104 Peripheral Nervous System Development 112 Neurulation 118 Neurogenesis 126 Cell Fate Determination 134 Neuronal Migration 142 Formation of the Cerebral Cortex 148 Proprioception 158 Spinothalamic Pathway 168 Nociception 178 Olfaction 186 Audition 194 Vision 204 Movement Control 214 Basal Ganglia 224 The Cerebellum 232 Eye Movements 242 Regulatory Functions of the Hypothalamus 250 The Neuroendocrine Axis 258 Thermoregulation 266 The Sympathetic Nervous System 274 The Parasympathetic Nervous System 282 Sleep and the Limbic System 290 The Reticular-Activating System 298 Neural Control of Respiration 304 Addiction 310 Axonal Injury 316 Nerve Growth Factors 324 Neural Stem Cells 332 Neural Repair 340 Brain Laterality 348 Visual Perception 356 Spatial Cognition 364 Language Disorders 370 Memory 378 Disconnection Syndromes 386 Executive Function 394 Consciousness 400 Intracerebral Hemorrhage and Increased Intracranial Pressure 406 Section III: Listing of Cases 414 Listing by Case Number 416 Listing by Disorder (Alphabetical) 417 Index 420 A 420 B 421 C 421 D 423 E 423 F 424 G 424 H 425 I 425 J 426 K 426 L 426 M 427 N 427 Q 428 P 429 Q 430 R 430 S 431 T 432 U 433 W 433 X 433 Helps yout to learn Biochemistry in the context of real-life patients and prepare for the USMLE. This title provides 53 true-to-life cases that illustrate essential concepts in this field. It includes a discussion correlated to essential basic science concepts, definitions of key terms, biochemistry pearls, and USMLE-style review questions. Case files: Neuroscience provides 49 true-to-life cases that illustrate essential concepts in this field. Each case includes an easy to understand discussion correlated to essential basic science concepts, definitions of key terms, neuroscience pearls, and USMLE-style review questions Case Files Neuroscience, 2e teaches students essential basic science concepts and their clinical application in the context of real patient scenarios -- so students learn rather than memorize. Helps you learn biochemistry in the context of real-life patients and prepare for the USMLE step 1. This book provides 53 true-to-life cases that illustrate essential concepts in this field