Case Studies in Infectious Diseases

Case Studies in Infectious Disease presents forty case studies featuring the most important human infectious diseases worldwide. Written for students of microbiology and medicine this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, followed by clinical presentation, diagnosis and treatment. Five core sets of questions are posed in each case. What is the nature of the infectious agent, how does it gain access to the body, what cells are infected, and how does the organism spread? What are the host defense mechanisms against the agent and how is the disease caused? What are the typical manifestations of the infection and the complications that can occur? How is the infection diagnosed and what is the differential diagnosis? How is the infection managed, and what preventative measures can be taken to avoid infection? This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms, fully integrating microbiology and immunology throughout.

Case Studies in Infectious Disease presents forty case studies featuring the most important human infectious diseases worldwide. Written for students of microbiology and medicine, this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis and treatment. The use of real clinical cases serves to reinforce and extend the basic science.

This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms, fully integrating microbiology and immunology throughout.

Doody Review Services

Reviewer:Trevor C Van Schooneveld, MD(University of Nebraska Medical Center )
Description:This book presents 40 case descriptions of diseases caused by bacterial, fungal, viral, and parasitic organisms which cause common or significant infections throughout the world. The presentation is arranged by organism, with an initial illustrative case followed by an exposition describing five key issues: the causative agent and its spread, the host response and pathogenesis of disease, the clinical presentation and complications, how the disease is diagnosed, and, finally, how the disease is treated and prevented.
Purpose:The authors, inspired by their successful medical school course, set out to create a book which would help students of microbiology and medicine understand a broad diversity of medically important organisms. They have been successful in this as they have included many key organisms and also described many key clinical syndromes of infectious disease in the process.
Audience:The nature of a case series book like this limits its use as a reference for medical trainees. However, it excels at providing a case-based introduction to the key epidemiologic, pathophysiologic, clinical, diagnostic, and treatment issues involved in a variety of infectious diseases and would be an excellent guide for case discussions in a medical microbiology course.
Features:The many clinical images, charts, tables, and diagrams that illustrate the text include excellent representations of clinical disease and clear descriptions of complicated biological systems. All images are available as JPEG images or PowerPoint slides on the publisher's website. Each chapter includes 1 to 2 pages of bulleted points which provide a concise summary of the material. Websites, including sites such as Wikipedia, are provided for further reference, but their utility varies. Finally, a series of multiple choice questions with answers and explanations are included with each chapter.
Assessment:This book, while far from definitive, provides an excellent resource for students of microbiology and medicine. It provides excellent descriptions, in text, pictures, and diagrams, of a broad spectrum of infectious diseases. While the level of detail may not satisfy experts in the field, the summary of complex information in concise text and graphics makes it a useful addition to most collections.

Book Cover......Page 1 Title......Page 4 Copyright......Page 5 Preface......Page 6 Acknowledgments......Page 7 Table of Contents......Page 8 Pathogens by type and body systems affected......Page 9 Case 1: Aspergillus fumigatus......Page 12 Case 2: Borrelia burgdorferi and related species......Page 30 Case 3: Campylobacter jejuni......Page 44 Case 4: Chlamydia trachomatis......Page 52 Case 5: Clostridium difficile......Page 74 Case 6: Coxiella burnetii......Page 84 Case 7: Coxsackie B virus......Page 110 Case 8: Echinococcus spp.......Page 118 Case 9: Epstein-Barr virus......Page 126 Case 10: Escherichia coli......Page 140 Case 11: Giardia lamblia......Page 150 Case 12: Helicobacter pylori......Page 160 Case 13: Hepatitis B virus......Page 172 Case 14: Herpes simplex virus 1 (HSV-1)......Page 188 Case 15: Herpes simplex virus 2 (HSV-2)......Page 198 Case 16: Histoplasma capsulatum......Page 208 Case 17: Human immunodeficiency virus (HIV)......Page 228 Case 18: Influenza virus......Page 246 Case 19: Leishmania spp.......Page 260 Case 20: Leptospira spp.......Page 272 Case 21: Listeria monocytogenes......Page 280 Case 22: Mycobacterium leprae......Page 288 Case 23: Mycobacterium tuberculosis......Page 302 Case 24: Neisseria gonorrhoeae......Page 314 Case 25: Neisseria meningitidis......Page 326 Case 26: Norovirus......Page 340 Case 27: Parvovirus......Page 350 Case 28: Plasmodium spp.......Page 358 Case 29: Respiratory syncytial virus (RSV)......Page 372 Case 30: Rickettsia spp.......Page 382 Case 31: Salmonella typhi......Page 394 Case 32: Schistosoma spp.......Page 404 Case 33: Staphylococcus aureus......Page 414 Case 34: Streptococcus mitis......Page 430 Case 35: Streptococcus pneumoniae......Page 440 Case 36: Streptococcus pyogenes......Page 450 Case 37: Toxoplasma gondii......Page 464 Case 38: Trypanosoma spp.......Page 474 Case 39: Varicella-zoster virus......Page 486 Case 40: Wuchereria bancrofti......Page 496 Glossary......Page 506 Answers to Multiple Choice Questions......Page 524 Figure Acknowledgments......Page 577 A ......Page 584 B ......Page 585 C ......Page 586 D ......Page 589 E ......Page 590 F ......Page 591 G ......Page 592 H ......Page 593 I ......Page 595 L ......Page 597 M ......Page 599 N ......Page 600 P ......Page 602 R ......Page 604 S ......Page 605 T ......Page 607 Z ......Page 609 "Case Studies in Infectious Disease presents forty case studies featuring the most important human infectious diseases worldwide. Written for students of microbiology and medicine this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, followed by the clinical presentation, diagnosis and treatment." "Five core sets of questions are posed in each case. What is the nature of the infectious agent, how does it gain access to the body, what cells are infected, and how does the organism spread? What are the host defense mechanisms against the agent and how is the disease caused? What are the typical manifestations of the infection and the complications that can occur? How is the infection diagnosed and what is the differential diagnosis? How is the infection managed, and what prevention measures can be taken to avoid infection?" "This standardized approach provides the reader with a logical basis for understanding these diverse and medically important organisms, fully integrating microbiology and immunology throughout." --Jacket Presents forty case studies featuring some of the most important human infectious diseases worldwide. Suitable for students of microbiology and medicine, this book describes the natural history of infection from point of entry of the pathogen through pathogenesis, clinical presentation, diagnosis and treatment