Cell culture and its application: [proceedings]

Cell Culture and Its Application covers the proceedings of the First International Cell Culture Congress Symposium, which focuses on how cell culture technology could impact on cell biology. The symposium aims to establish facilities for the cultivation of mammalian cells, which in turn would hopefully enhance basic cell biology research. The book is organized into four symposium and workshop sessions, encompassing 45 chapters. The opening chapter recognizes the interlocking relationship of cell culture technology and substantive cell biology. Chapters 2-5 describe the biochemical events that mark the cell cycle, with emphasis on occurrence of histone phosphorylation at each cycle. A discussion on cell differentiation, as a phenomena of interacting, inductive, and inhomogeneous cell populations, is included in these chapters. The second symposium session deals with signs of a revolution in progress in cell culture technology. This includes impact of tissue culture in physiological research course and in understanding of integrated physiology. The last two symposium sessions cover the large-scale production of virus from tissue cultures for cell antigens. An approach to the study of aging using diploid human cells in culture as a model system is also presented. It involves isolation and characterization of HLA antigens from cultured cells and their contribution to the study of disease. A brief discussion on mycoplasma contamination, microplasma-cell-virus interaction, and advantages and limitations of direct and indirect culture for primary isolation and detection of mycoplasma contamination is provided. The book then proceeds by discussing cell differentiation of specific cell or organ, such as testis, sensory cell, hepatocyte, embryonic muscle cell, and brain cortex. The concluding chapters cover nutritional requirements for cell growth, defined culture media for specific cell type, issues and problems related to large-scale cell production, and quality control. Cell biologists and researchers will find this book invaluable. Content: ORGANIZING COMMITTEE , Page ii Front Matter , Page iii Copyright , Page iv LIST OF CONTRIBUTORS , Pages xi-xvi PREFACE , Pages xvii-xviii OPENING REMARKS , Pages 1-2 , HERMAN W. LEWIS SEQUENTIAL BIOCHEMICAL EVENTS IN THE CELL CYCLE , Pages 5-22 , Robert A. Tobey, Ronald A. Walters, Philip G. Hohmann, Carl E. Hildebrand, Lawrence R. Gurley AGGREGATE CULTURES: A MODEL FOR STUDIES OF BRAIN DEVELOPMENT , Pages 23-37 , Nicholas W. Seeds, Galo Ramirez, Michael J. Marks DIFFERENTIATION OF T CELLS IN VITRO , Pages 39-47 , GIDEON GOLDSTEIN SUMMARY REMARKS OF CHAIRMAN , Pages 49-51 , PHILIP COFFINO FIBROBLAST GROWTH FACTOR: EFFECT ON GROWTH OF FIBROBLASTS AND RELATED CELL TYPES , Pages 55-81 , DENIS GOSPODAROWICZ, JOHN S. MORAN HUMAN EPIDERMAL GROWTH FACTOR , Pages 83-105 , GRAHAM CARPENTER, STANLEY COHEN SUMMARY REMARKS , Pages 107-108 , GORDON SATO PROBLEMS ENCOUNTERED IN LARGE SCALE CELL PRODUCTION PLANTS , Pages 111-127 , H.C. GIRARD LARGE-SCALE PRODUCTION OF MURINE LYMPHOBLASTOID CELL: LINES EXPRESSING DIFFERENTIATION ALLOANTIGENS , Pages 129-160 , RONALD T. ACTON, PAUL A. BARSTAD, R. MICHAEL COX, ROBERT K. ZWERNER, KIM S. WISE, J. DANIEL LYNN COMPUTER CONTROL OF MAMMALIAN CELL SUSPENSION CULTURES , Pages 161-189 , LASZLO K. NYIRI OPTIMIZING PARAMETERS FOR GROWTH OF ANCHORAGE-DEPENDENT MAMMALIAN CELLS IN MICROCARRIER CULTURE , Pages 191-216 , D.W. LEVINE, D.I.C. WANG, W.G. THILLY SUMMARY REMARKS , Pages 217-220 , J.J. CALLIS REGULATION OF PROLIFERATIVE CAPACITY DURING AGING IN CELL CULTURE , Pages 223-245 , V.J. CRISTOFALO, J.M. RYAN, G.L. GROVE ISOLATION AND CHARACTERISATION OF HLA ANTIGENS FROM CULTURED CELLS AND THEIR CONTRIBUTION TO THE STUDY OF DISEASE , Pages 247-266 , DAVID SNARY, MICHAEL J. CRUMPTON, PETER GOODFELLOW, WALTER F. BODMER NEW APPROACHES TO HUMAN LYSOSOMAL STORAGE DISEASES USING ANIMAL CELLS AND ANIMAL VIRUSES , Pages 267-282 , WILLIAM S. SLY SUMMARY REMARKS: ROLE OF CELL CULTURE IN THE STUDY OF DISEASE , Pages 283-287 , JERE P. SEGREST MYCOPLASMA CONTAMINATION OF CELL CULTURES: A STATUS REPORT , Pages 291-334 , MICHAEL F. BARILE RECENT STUDIES – RNA TUMOR VIRUSES , Pages 335-343 , RAYMOND V. GILDEN CELL DIFFERENTIATION OF JUVENILE CHICK TESTIS II. CONVERSION OF PROGESTERONE TO TESTOSTERONE IN VITRO , Pages 347-361 , HAROLD H. LEE, LORETTA LIANG-TANG, NORIMOTO KAZAMA DIFFERENTIATION OF SENSORY CELLS IN CULTURES OF AGGREGATES OF DISSOCIATED EMBRYONIC CHICK OTOCYSTS , Pages 363-377 , MARY FAITH ORR A MODEL FOR THE “PERMISSIVE” EFFECT OF GLUCOCORTICOIDS ON THE GLUCAGON INDUCTION OF AMINO ACID TRANSPORT IN CULTURED HEPATOCYTES , Pages 379-388 , MICHAEL W. PARIZA, ROLF F. KLETZIEN, VAN R. POTTER CYTOPLASMIC MESSENGER RIBONUCLEOPROTEINS AND TRANSLATIONAL CONTROL DURING GROWTH AND DIFFERENTIATION OF EMBRYONIC MUSCLE CELLS , Pages 389-416 , SATYAPRIYA SARKAR, JNANANKUR BAG EXPLANTS OF NEWBORN RAT BRAIN CORTEX SHOW MUTUAL INFLUENCE OF FATTY ACID PATTERNS AFTER COMBINATION AT DIFFERENT AGES IN ORGANOTYPIC CULTURES , Pages 417-432 , M. GIESING, F. ZILLIKEN USE OF IN VITRO CELL COLONY ASSAYS FOR MEASURING THE CYTOTOXICITY OF CHEMOTHERAPEUTIC AGENTS TO HEMATOPOIETIC PROGENITOR CELLS COMMITTED TO MYELOID, ERYTHROID AND MEGAKARYOCYTOID DIFFERENTIATION , Pages 433-448 , ALEXANDER NAKEFF, FREDERICK A. VALERIOTE MELANOGENESIS IN SOMATIC CELL HYBRIDS , Pages 449-459 , FUNAN HU, LINDA M. PASZTOR MORPHOLOGICAL TRANSFORMING FACTOR: INFLUENCE ON HISTOTYPIC ORGANIZATION OF EPITHELIAL BRAIN CELLS , Pages 461-480 , RAMON LIM, DAVID E. TURRIFF, SHUANG S. TROY, KATSUSUKE MITSUNOBU ALTERATIONS IN THE PHENOTYPIC EXPRESSION OF CULTURED ARTICULAR CHONDROCYTES BY A PITUITARY GROWTH FACTOR (CGF) , Pages 481-490 , CHARLES J. MALEMUD, DAVID P. NORBY RESTORATION OF PIGMENT SYNTHESIS IN MUTANT MELANOCYTES AFTER FUSION WITH CHICK EMBRYO ERYTHROCYTES , Pages 491-500 , D.G. SCHALL, J.A. BRUMBAUGH THE SERINE AND GLYCINE REQUIREMENTS OF CULTURED HUMAN LYMPHOCYTE LINES , Pages 503-511 , J.R. BIRCH, D.W. HOPKINS AUTOCLAVABLE LOW COST CELL CULTURE MEDIA , Pages 513-532 , LEONARD KEAY QUALITATIVE AND QUANTITATIVE ANALYSIS OF NUTRITIONAL FACTORS FOR CELL GROWTH , Pages 533-540 , RICHARD G. HAM, PATRICIA M. SULLIVAN SALINE WASHES STIMULATE THE PROLIFERATION OF HUMAN FIBROBLASTS IN CULTURE , Pages 541-555 , JAMES C. LACEY JR., JANNA D. STROBEL, DANIEL P. STEPHENS JR. TISSUE CULTURE REAGENT QUALITY ASSURANCE TESTING IN A LARGE-SCALE VIRUS PRODUCTION LABORATORY , Pages 559-570 , CHARLES V. BENTON, ROGER W. JOHNSON, ALBERT PERRY, W.I. JONES, GEORGE P. SHIBLEY CONTAMINATION MONITORING AND CONTROL IN A LARGE SCALE TISSUE CULTURE VIRUS PRODUCTION LABORATORY , Pages 571-587 , ROGER W. JOHNSON, CHARLES V. BENTON, ALBERT PERRY, JOHN HATGI, GEORGE P. SHIBLEY MASS CELL CULTURES IN A CONTROLLED ENVIRONMENT , Pages 589-601 , MONA D. JENSEN GROWTH OF BHK CELLS FOR THE PRODUCTION AND PURIFICATION OF FOOT-AND-MOUTH DISEASE VIRUS , Pages 603-615 , J. POLATNICK, H.L. BACHRACH SIGNIFICANCE OF OXIDATION-REDUCTION POTENTIAL IN MAMMALIAN CELL CULTURES , Pages 617-635 , G.M. Toth HUMAN CELL CULTURES AS SENTINEL SYSTEMS FOR MONITORING AIR QUALITY , Pages 637-650 , ERNEST V. ORSI, PETER LEVINS, GREGORY AMES, LOIS BUONINCONTRI, NESTOR HOLYK, RYTIS BALCIUNAS FAT BODY CULTURE SYSTEMS IN THE STUDY OF FROG DISEASES , Pages 653-666 , ROBERT L. AMBORSKI, GRACE F. AMBORSKI MICROASSAY OF BLUETONGUE VIRUS FROM CULICOIDES VARIIPENNIS , Pages 667-674 , B.M. BANDO, R.H. JONES HUMAN COLORECTAL CELL LINES AS A SOURCE FOR CARCINOEMBRYONIC ANTIGEN (CEA) , Pages 675-687 , ALBERT LEIBOVITZ, WILLIAM B. MCCOMBS, CAMERON E. MCCOY, KENNETH C. MAZUR, NANCY D. MABRY, JAMES C. STINSON THE ELABORATION OF GLYCOPROTEINS INTO CULTURE MEDIUM BY HUMAN OVARIAN TUMOR CELLS , Pages 689-709 , H.J. ALLEN, J.J. BARLOW, E.A.Z. JOHNSON ESTABLISHMENT AND CHARACTERIZATION OF EPITHELIAL CELL CULTURES FROM TUMORS OF THE HUMAN URINARY TRACT , Pages 711-728 , A.Y. ELLIOTT, D.L. BRONSON, J. CERVENKA, P.H. CLEVELAND, E.E. FRALEY CARDIAC MUSCLE CELL CULTURE AS A PHARMACOLOGICAL TOOL: THE EFFECT OF CORONARY DILATORS ON THE METABOLISM OF ADENOSINE , Pages 729-752 , S. JAMAL MUSTAFA The First International Cell Culture Congress, Birmingham, Alabama, September 21-25, 1975 ; Organizing Committee, Ronald T. Acton, Chairman ... [et Al.] ; Advisory Committee, Herman Lewis, Jerry J. Callis, Leonard Keay ; Edited By Ronald T. Acton, J. Daniel Lynn. Includes Bibliographies.