Cell Hybrids

Content: Front Matter, Page iii Copyright, Page iv Preface, Pages ix-x List of Abbreviations, Pages xi-xiv I - Introduction, Pages 1-5 II - History, Pages 6-14 III - Spontaneous Cell Fusion, Pages 15-28 IV - Virus-Induced Cell Fusion, Pages 29-45 V - Mechanism of Cell Fusion, Pages 46-63 VI - Fusion of Cells at Different Stages of the Cell Cycle, Pages 64-86 VII - Heterokaryons, Pages 87-118 VIII - Fusion with Cell Fragments, Pages 119-146 IX - Isolation of Growing Hybrid Cells, Pages 147-161 X - Chromosome Patterns in Hybrid Cells, Pages 162-179 XI - Phenotypic Expression in Hybrid Cells, Pages 180-212 XII - Cell Organelles in Hybrid Cells, Pages 213-223 XIII - Gene Mapping and Gene Complementation Analysis, Pages 224-244 XIV - Analysis of Malignancy by Cell Hybridization, Pages 245-270 XV - Viral Infection and Somatic Cell Hybrids, Pages 271-289 XVI - Plant Cell Hybrids, Pages 290-300 Bibliography, Pages 301-348 Glossary, Pages 349-356 Index, Pages 357-366 Cell Hybrids summarizes the methodology of cell fusion-the fusion of human, animal, and plant cells of different origins to produce cell hybrids-and surveys the main applications and current findings of the hybridization technique. The book opens with a chapter on the history cell hybridization. This is followed by separate chapters on spontaneous cell fusion, virus-induced cell fusion, the cell fusion mechanism, regulation of DNA synthesis and mitosis in heterokaryons and homokaryons, and regulatory events which occur when two cells with different nuclear activity and/or phenotype are fused w ..