Cellular Nanomachines : From Discovery to Structure-Function and Therapeutic Applications

In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology. Front Matter ....Pages i-xviii Porosome: Cells Secretory Nanomachine (Bhanu P. Jena)....Pages 1-39 Ubiquitin–Proteasome Machinery: Cells Garbage Disposal (Bhanu P. Jena)....Pages 41-47 Chaperonin: Protein Folding Machinery in Cells (Bhanu P. Jena)....Pages 49-56 ATP Synthase: Energy Generating Machinery in Cells (Bhanu P. Jena)....Pages 57-62 Ribosome: Cells Protein Synthetic Machinery (Bhanu P. Jena)....Pages 63-69 Nuclear Pore: A Bidirectional Transport Machinery (Bhanu P. Jena)....Pages 71-77 Myosin: Cellular Molecular Motor (Bhanu P. Jena)....Pages 79-89 Assembly of Cellular Nanomachines (Bhanu P. Jena)....Pages 91-104 Back Matter ....Pages 105-109