Concepts in Viral Pathogenesis II

Front Matter....Pages i-xix Front Matter....Pages 1-1 The Three-dimensional Structure of Poliovirus: Implications for Virus Evolution, Assembly, and Immune Recognition....Pages 3-14 The Three-dimensional Structure of Surface Antigens from Animal Viruses....Pages 15-24 Using Nucleotide Sequence Determination to Understand Viruses....Pages 25-31 Viruses with Ambisense RNA Genomes....Pages 32-39 Human Respiratory Syncytial Virus Genome and Gene Products....Pages 40-46 Front Matter....Pages 47-47 Bovine Papillomavirus DNA Vectors....Pages 49-56 Genetic Engineering of Vaccinia Virus Vectors: Development of Live Recombinant Vaccines....Pages 57-60 Viral Enhancer Elements....Pages 61-67 Front Matter....Pages 69-69 Amplification of Proto-oncogenes in Tumorigenesis....Pages 71-78 Multistep Scenarios in Tumor Development and the Role of Oncogene Activation by Chromosomal Translocations....Pages 79-88 Oncogene Activation by Chromosome Translocation....Pages 89-97 Oncogenes, Growth Factors, and Receptors....Pages 98-109 Specificity of Viral Gene Controlling Elements in Transgenic Mice....Pages 110-113 Front Matter....Pages 115-115 Isolation of Cellular Receptors for Viruses....Pages 117-125 Viral Receptors Serving Host Functions....Pages 126-131 Genetics of Retrovirus Tumorigenicity....Pages 132-140 Adenovirus Entry into Cells: Some New Observations on an Old Problem....Pages 141-146 Molecular Anatomy of Viral Infection: Study of Viral Nucleic Acid Sequences and Proteins in Whole Body Sections....Pages 147-156 Front Matter....Pages 157-157 Mapping Neutralization Domains of Viruses....Pages 159-173 CTL Recognition of Transfected H-2 Gene and Viral Gene Products....Pages 174-181 Front Matter....Pages 157-157 Heterogeneity of CTL Reactive Antigenic Sites on SV40 Tumor Antigen....Pages 182-186 Virus-specific HLA Class II-restricted Cytotoxic T Cells....Pages 187-192 Front Matter....Pages 193-193 Molecular Mimicry....Pages 195-202 Virus-induced Autoimmune Demyelinating Disease of the Central Nervous System....Pages 203-209 Front Matter....Pages 211-211 The Enigma of Viroid Pathogenesis....Pages 213-220 Prions Causing Scrapie and Creutzfeldt-Jakob Disease....Pages 221-231 Interferon-induced Disease....Pages 232-242 African Swine Fever Virus....Pages 243-247 Theiler’s Murine Encephalomyelitis Virus (TMEV) Infection in Mice as a Model for Multiple Sclerosis....Pages 248-254 Front Matter....Pages 255-255 Human T Cell Lymphotropic Viruses and Their Family of Diseases....Pages 257-260 Pathogenesis of Parvovirus-induced Disease in Humans....Pages 261-268 Hepatitis B Virus and Cancer....Pages 269-275 Progressive Epstein-Barr Virus Infection....Pages 276-286 Human Papillomaviruses: Why Are Some Types Carcinogenic?....Pages 287-297 Front Matter....Pages 299-299 Nucleic Acid Probes to Detect Viral Diseases....Pages 301-309 In Situ Hybridization and Covert Virus Infections....Pages 310-316 Oligonucleotide Fingerprinting in the Investigations of Outbreaks of Viral Disease....Pages 317-323 Monoclonal Antibodies as Reagents....Pages 324-330 Anti-peptide Antibodies: Some Practical Considerations....Pages 331-335 Front Matter....Pages 337-338 Eradication and Possible Reintroduction of Smallpox....Pages 339-345 Front Matter....Pages 337-338 Immunogenicity of Vaccine Products and Neutralizing Antibodies....Pages 346-353 Prospects for Development of a Vaccine Against HTLV-III Disease....Pages 354-364 Prospects for a Varicella-Zoster Vaccine....Pages 365-371 Prospects for Treatment and Prevention of Latent Herpes Simplex Virus Infection....Pages 372-379 Prospects for Improved Immunization Against Influenza....Pages 380-387 Cleavage Site Mutant As a Potential Vaccine....Pages 388-393 Prospects for a Synthetic Foot-and-Mouth Disease Vaccine....Pages 394-400 Anti-idiotype Vaccines Against Viral Infections....Pages 401-411 Chemotherapy of Lassa Virus Infection....Pages 412-416 Back Matter....Pages 417-425