[Contents] 1: Understanding the Fundamental Nature of Information and its Processing. -- 2: A Few Questions on Information Sharing. -- 3: The Place of Healthcare Delivery Processes in Information Systems. -- 4: The Quality of the Urbanization of the Information System is Central to its Performance. -- 5: Reference Terminologies in Healthcare Information Systems. -- 6: Patient Identification in Healthcare Information Systems. -- 7: Information System Security and Data Protection. -- 8: Knowledge Management and Medical Decision Support. -- 9: Managing and Integrating Clinical Data: Health Records. -- 10: Managing and Integrating Laboratory Data and Functional Investigations. -- 11: Managing and Integrating Medical Images. -- 12: Managing and Integrating Telemedicine and Telehealth. -- 13: Integrating Extra-hospital Care Data. -- 14: Reusing Data in Healthcare. -- 15: Integrating Data for Management and Decision Analysis. -- 16: Data for Epidemiology and Public Health, and Big Data. -- 17: Integrating Bioinformatics Data. -- 18: Clinical Research Data. -- 19: Evaluating Information Systems. -- 20: The Governance of Healthcare Information Systems, the Hospital, Outpatient and Industrial Contexts. -- Appendix 1: Management of Selected International Terminologies. -- Appendix 2: Further Information on DICOM Standards. -- Appendix 3: Further Information on the système national des données de santé (National Healthcare Data System - SNDS) in France. -- Appendix 4: Metadata. -- Appendix 5: Clinical Observation Specifications. -- Appendix 6: Ontologies. -- Appendix 7: Document Banks - Medication Data. -- Appendix 8: Hosting Health Data in France. -- Appendix 9: Developing an Information System Master Plan Health Data Processing: Systemic Approaches focuses on the design of health information systems and touches on the main themes of medical informatics and public health. The book is written for health professionals in practice or training, and is especially useful for decision-makers or future decision-makers in the field of health information systems. Users will find sections on the question of reusing data for other purposes, protection of individual liberties that this data and technologies make more acute, and the irruption of large masses of genetic data and its related problems. This book develops the methodological and conceptual aspects related to these issues. Proposes a methodology for the development of health information systems for the better use of digital technologies Illustrates a systemic, transversal, conceptual vision that supports the complex reality of the healthcare world, where the interoperability of agents (professionals and software) is central Discusses the reuse of resources of data for knowledge improvement, health security and public health