Heart development (1st Edition)

This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and that the heart develops similarly across all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects. Key Features* Each chapter has been solicited from a recognized leader in the field, and covers a topic of active research in cardiovascular biology* Chapters incorporate a review of classical findings with comprehensive coverage of the latest advances* Abundant color plates in a consistent and professional artistic style provide clear and attractive illustrations of central concepts* Color slides of illustrations for seminars or teaching purposes are available with each volume CoverPage......Page 1 BackCover......Page 2 FrontMatter......Page 3 Frontispiece......Page 4 TitlePage......Page 5 CopyRight......Page 6 Dedication......Page 7 Contents......Page 9 Contributors......Page 15 Preface......Page 19 Introduction......Page 21 1 - Cardiac Fate Maps......Page 25 2 - Cardiac Lineages......Page 41 3 - Heart Formation and the Heart Field in Amphibian Embryos......Page 59 4 - Vertebrate Heart Induction......Page 73 5 - Genetic Determination of Drosophila Heart Development......Page 87 6 - Mutations Affecting Cardiac Development in Zebrafish......Page 113 7 - Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart......Page 133 8 - Control of Cardiac Development by the MEF2 Family of Transcription Factors......Page 153 9 - Segmental Regulation of Cardiac Development by the bHLH TFs dHAND and eHAND......Page 165 10 - Mechanisms of Segmentation, Septation & Remodeling of the Tubular Heart......Page 181 11 - Contribution of Neural Crest to Heart and Vessel Morphology......Page 201 12 - Development of the Conduction System of the Vertebrate Heart......Page 217 13 - Retinoids in Heart Development......Page 231 14 - Molecular Mechanisms of Vascular Development......Page 243 15 - The MLC-2 Paradigm for Ventricular Heart Chamber Specification, Maturation, and Morphogenesis......Page 277 16 - Serum Response Factor-NK Homeodomain Factor Interactions, Role in Cardiac Development......Page 295 17 - GATA Transcription Factors and Cardiac Development......Page 313 18 - Multiple Layers of Control in Transcriptional Regulation by MCAT Elements and the TEF-1 Protein Family......Page 329 19 - Regionalization of Transcriptional Potential in the Myocardium......Page 355 20 - Chamber-Specific Gene Expression and Regulation during Heart Development......Page 379 21 - Establishing Cardiac Left-Right Asymmetry......Page 395 22 - Left-Right Asymmetry and Cardiac Looping......Page 413 23 - The Cardiac Cell Cycle......Page 427 24 - Regulation of Vascular Smooth Muscle Differentiation and Cell Cycle......Page 451 25 - Symmetry and Laterality in the Human Heart - Developmental Implications......Page 469 26 - The Genetic Basis of Conotruncal Cardiac Defects - The Chromosome 22q11.2 Deletion......Page 485 27 - Genetics of Human Left-Right Axis Malformations......Page 501 28 - Molecular Genetics of Skeletal Muscle Development......Page 515 Index......Page 541 Origins And Early Morphogenesis -- Cardiac Induction -- Genetic Dissection Of Heart Development -- Normal And Abnormal Morphogenesis -- Genetic Control Of Muscle Gene Expression -- Heart Patterning: The Anterior-posterior Axis -- Heart Patterning: Left-right Asymmetry -- Cell Proliferation In Cardiovascular Development And Disease -- Human Cardiac Development Defects -- Lessons From Skeletal Muscle. Edited By Richard P. Harvey, Nadia Rosenthal. Includes Bibliographical References And Index. This book examines recent studies revealing that the same genes are responsible for development of parallel features between species, and the heart develops exactly the same in all species. It includes research being conducted concerning cardiac development, tissue interaction, and organ formation. The text attempts to provide a greater understanding of the underlying causes of heart failure, heart muscle diseases, congenital malformations, and other heart diseases and defects.