Hepatocellular Carcinoma - Basic Research

00 preface_Hepatocellular Carcinoma – Basic Research......Page 1 01aPart1......Page 11 01_LAPTM4B: A Novel Diagnostic Biomarker and Therapeutic Target for Hepatocellular Carcinoma......Page 13 02_Novel Therapeutic Targets for Hepatocellular Carcinoma Treatment......Page 45 03_Clinical Significance of Serum Ornithine Carbamoyltransferase in Liver Diseases; is the Ratio of OCT/ALT a New Tumor Marker?......Page 71 04_New Molecular Biomarkers Candidates for the Development of Multiparametric Platforms for Hepatocellular Carcinoma Diagnosis, Prognosis and Personalised Therapy......Page 83 05aPart 2......Page 111 05_Modulation of Cell Proliferation Pathways by the Hepatitis B Virus X Protein: A Potential Contributor to the Development of Hepatocellular Carcinoma......Page 113 06_Vascular Adhesion Protein-1 and Hepatocellular Cancer......Page 163 07_Tissue Factor Pathway Inhibitor-2 Inhibits the Growth and Invasion of Hepatocellular Carcinoma Cells and is Inactivated in Human Hepatocellular Carcinoma......Page 171 08-Proteoglycans in Chronic Liver Disease and Hepatocellular Carcinoma: An Update......Page 181 09_Chemically Induced Hepatocellular Carcinoma and Stages of Development with Biochemical and Genetic Modulation: A Special Reference to Insulin-Like-Growth Factor II and Raf Gene Signaling......Page 211 10_Hepatocellular Carcinoma: Insights from the Centrosome Abnormalities......Page 229 11_Cytoplasmic Connexin32 and Self-Renewal of Cancer Stem Cells: Implication in Metastasis......Page 245 12_The Involvement of the ERK-Hypoxia- Angiogenesis Signaling Axis and HIF-1 in Hepatocellular Carcinoma......Page 263 13_Gap Junction Intercellular Communication and Connexin Expression Profile in Normal Liver Cells and Hepatocarcinoma......Page 285 14_Mechanisms of HBx Mediated Liver Cancer: Multiple Pathways and Opportunities......Page 297 15_Molecular Mechanism of DNA Damage Response Pathway During Hepatic Carcinogenesis......Page 323 16aPart 3......Page 335 16_Hepatocellular Carcinoma: Methods of Circulating Tumor Cells (CTC) Measurements......Page 337 17_Use of a Human–Derived Liver Cell Line for the Detection of Protective Effect of Dietary Antioxidants against Food Mutagens......Page 367 18_Reviews on the Epidemiology, Quality of Life, and Management of Chronic Hepatitis B (CHB)......Page 383 Hepatocellular Carcinoma Represents A Leading Cause Of Cancer Death And A Major Health Problem In Developing Countries Where Hepatitis B Infection Is Prevalent. It Has Also Become Increasingly Important With The Increase In Hepatitis C Infection In Developed Countries. Knowledge Of Hepatocellular Carcinoma Has Progressed Rapidly. This Book Is A Compendium Of Papers Written By Experts To Present The Most Up-to-date Knowledge On Hepatocellular Carcinoma. This Book Deals Mainly With The Basic Research Aspect Of Hepatocellular Carcinoma. The Book Is Divided Into Three Sections: (i) Biomarkers / Therapeutic Target; (ii) Carcinogenesis / Invasion / Metastasis; And (iii) Detection / Prevention / Prevalence. There Are 18 Chapters In This Book. This Book Is An Important Contribution To The Basic Research Of Hepatocellular Carcinoma. The Intended Readers Of This Book Are Scientists And Clinicians Who Are Interested In Research On Hepatocellular Carcinoma. Epidemiologists, Pathologists, Hospital Administrators And Drug Manufacturers Will Also Find This Book Useful.