This book provides an update of the first edition, which is recognized as the definitive reference on insect repellents. The Second Edition reflects the current state of insect repellent science. It covers the processes involved in the development and testing of new active ingredients and formulations, and discusses the practical uses of repellents. It is a resource that will be useful to a wide variety of professionals including insect repellent researchers, medical entomologists, public health and medical personnel, industry and sales professionals, government regulators, and wildlife scientists and managers. Front Cover 1 My dear three brothers and four sisters; my beautiful and loving wife, Natalie, and our wonderful children: Ameena, Adam, and David; and to the memory of my beloved parents. 6 Contents 8 Preface 12 Acknowledgments 14 Contributors 16 Chapter 1: Terminology of Insect Repellents 20 Chapter 2: Neuromolecular Basis of Repellent Action 48 Chapter 3: How Repellents Work : Neurophysiological and Behavioral Analyses 60 Chapter 4: In Silico Models for Development of Insect Repellents 70 Chapter 5: Can Green Chemistry Provide Effective Repellents? 92 Chapter 6: Excitorepellency 108 Chapter 7: Evaluation of Repellent Efficacy in Reducing Disease Incidence 134 Chapter 8: Testing Methods for Insect Repellents 176 Chapter 9: Plant-Based Insect Repellents 196 Chapter 10: Insect Repellents Derived from Australian Plants and Implications for Public Health Messages 230 Chapter 11: Topical Repellent Active Ingredients in Common Use 248 Chapter 12: Spatial or Area Repellents 256 Chapter 13: Marketing for Efficacy, Acceptability, Safety, and Health 270 Chapter 14: Klun & Debboun Modules: Uses and Data Analysis 284 Chapter 15: Use of Chemical Mixtures as Insecticides and Repellents 300 Chapter 16: Use of Repellents Formulated in Specialized Pheromone and Lure Application Technology for Effective Insect Pest Management 308 Chapter 17: Strategies for Using Personal Protection Products 334 Chapter 18: Best Practices for Use of Personal Protection Products 348 Chapter 19: Commercially Available Insect Repellents and Criteria for Their Use 356 Chapter 20: Alterations of Blood-Feeding Behavior and Repellent Response of Pathogen-Infected Biting Flies 368 Chapter 21: Insect Repellents for Other Potential Use 374 Chapter 22: Future of Insect Repellents 384 Appendix 388 Back Cover 400 The public has a great desire for products that prevent the annoyance of biting insects and ticks, but that desire does not always translate into sensible use of those products. Insect Repellents Handbook, Second Edition summarizes evidence-based information on insect repellents to inform decisions by those involved with insect repellent research, development, and use. This authoritative, single-source reference makes it possible for you to quickly gain a working level of expertise about insect repellents, without having to search through the scattered literature. The previous edition was the first comprehensive volume on this subject and quickly became the definitive reference on insect repellents. This second edition reflects the current state of insect repellent science, covers the processes involved in the development and testing of new active ingredients and formulations, and discusses the practical uses of repellents. The book includes thought-provoking discussions on how repellents work, their neuromolecular basis of action, and whether green chemistry can provide effective repellents. It also supplies an in-depth understanding of the development of repellents including testing methods, review of active ingredients, and the use of chemical mixtures as repellents. It provides science-backed chapters on repellent use including best practices for use of personal protection products, criteria for repellent use, and insect repellents for other potential use.
