Interferons [recurso electrónico] a primer

Interferons: A Primer covers general information on interferon, including analysis, purification, production, properties, mechanism of action, and clinical uses. Organized into 10 chapters, the book starts with a short history of interferon's discovery by Isaacs and Lindenmann, followed by topics on assays for interferon, such as factors affecting interferon assays and rapid biological assay. Chapters 3 to 6 discuss the purification, properties, production, antiviral action, and other functions of interferon. Chapters 7 and 8 examine the recovery from viral infection and clinical uses of interferon, with emphasis on treatment of human cancer. The concluding chapters focus on the application of interferon studies on two revolutionizing fields of biology, namely, the cloning of animal genes in microorganisms and the production of monoclonal antibodies. This book is intended for students, scientists, physicians, or educated laypersons who wish to know something about interferons, but do not plan carrying out research in this area. Content: Front Matter , Page iii Copyright , Page iv PREFACE , Pages ix-xii 1 - INTRODUCTION , Pages 1-7 2 - ASSAYS FOR INTERFERON , Pages 9-16 3 - PURIFICATION AND PROPERTIES OF INTERFERONS , Pages 17-24 4 - PRODUCTION OF INTERFERONS , Pages 25-45 5 - MECHANISMS OF ANTIVIRAL ACTION , Pages 47-71 6 - OTHER ACTIONS OF INTERFERONS , Pages 73-88 7 - INTERFERONS AND RECOVERY FROM VIRAL INFECTIONS , Pages 89-101 8 - CLINICAL USES OF INTERFERONS , Pages 103-115 9 - THE FUTURE OF INTERFERONS , Pages 117-124 10 - THE FUTURE IS NOW , Pages 125-131 GLOSSARY , Pages 133-143 INDEX , Pages 145-151