This book presents all effective and safe techniques in interstitial hyperthermia and gives examples of applications in areas of clinical interest. Interstitial hyperthermia has been preferentially accepted by oncologists because it can be easily combined with other forms of treatment. One of the principal advantages is the threedimensionally restricted heat deposition to the tumor site. The contributions in this book are written by experts in the fields of biology, physics, and clinical implementation. The technical and clinical state of the art as well as quality assurance in interstitial hyperthermia is presented and practical information for the oncologists working in this field is given. Front Matter....Pages I-VIII Brachytherapy and Hyperthermia: Biological Rationale....Pages 1-9 Simultaneous and Sequential Treatment with Radiation and Hyperthermia: A Comparative Assessment....Pages 11-33 Local Hyperthermia in Combination with Chemotherapeutic Agents....Pages 35-50 Physical Aspects of Interstitial Hyperthermia....Pages 51-75 Quality Assurance for Interstitial Radiofrequency-Induced Hyperthermia....Pages 77-94 Experience with Radiofrequency-Local Current Field Interstitial Hyperthermia: Biological Rationale, Equipment Development, and Clinical Results....Pages 95-119 Clinical Experience with Different Interstitial Hyperthermia Techniques....Pages 121-134 Clinical Practice of Interstitial Microwave Hyperthermia Combined with Iridium-192 Brachytherapy....Pages 135-154 Animal Experiments with Interstitial Water Hyperthermia....Pages 155-163 Simultaneous Application of Combined Interstitial High- or Low-Dose Rate Irradiation with Hot Water Hyperthermia....Pages 165-170 Interstitial Warm-Water Hyperthermia Combined with Ir 192-HDR Implantation: Principle, Practical Application and First Clinical Experiences....Pages 171-182 Interstitial Hyperthermia with Ferromagnetic Seed Implants: Preliminary Results of a Phase I Clinical Trial....Pages 183-193
