Islamic Biomedical Ethics : Principles and Application

Biomedical ethics is a burgeoning academic field with complex and far-reaching consequences. Whereas in Western secular bioethics this subject falls within larger ethical theories and applications (utilitarianism, deontology, teleology, and the like), Islamic biomedical ethics has yet to find its natural academic home in Islamic studies. In this pioneering work, Abdulaziz Sachedina - a scholar with life-long academic training in Islamic law - relates classic Muslim religious values to the new ethical challenges that arise from medical research and practice. He depends on Muslim legal theory, but then looks deeper than juridical practice to search for the underlying reasons that determine the rightness or wrongness of a particular action. Drawing on the work of diverse Muslim theologians, he outlines a form of moral reasoning that can derive and produce decisions that underscore the spirit of the Shari'a. These decisions, he argues, still leave room to revisit earlier decisions and formulate new ones, which in turn need not be understood as absolute or final. After laying out this methodology, he applies it to a series of ethical questions surrounding the human life-cycle from birth to death, including such issues as abortion, euthanasia, and organ donation. The implications of Sachedina's work are broad. His writing is unique in that it aims at conversing with Jewish and Christian ethics, moving beyond the Islamic fatwa literature to search for a common language of moral justification and legitimization among the followers of the Abrahamic traditions. He argues that Islamic theological ethics be organically connected with the legal tradition of Islam to enable it to sit in dialogue with secular and scripture-based bioethics in other faith communities. A breakthrough in Islamic bioethical studies, this volume is welcome and long-overdue reading for anyone interested in facing the difficult questions posed by modern medicine not only to the Muslim faithful but to the ethically-minded at large.

disorders Of The Nervous And Vascular Systems Continue To Burden The Planet's Population Not Only With Increasing Morbidity And Mortality, But Also With A Significant Financial Drain Through Increasing Medical Care Costs Coupled To A Progressive Loss In Economic Productivity. For Example, More Than 500 Million Individuals Suffer From Nervous And Vascular System Disorders In The World That Comprise Both Acute And Chronic Degenerative Diseases Such As Hypertension, Cardiac Insufficiency, Diabetes Mellitus, Stroke, Traumatic Brain Injury, And Alzheimer's Disease. Given The Vulnerability Of The Nervous And Vascular Systems, Identifying The Cellular Pathways That Determine Cellular Function, Injury, And Longevity May Significantly Assist In The Development Of Therapeutic Strategies To Either Prevent Or At Least Reduce Disability From Crippling Degenerative Disorders. With This Objective, neurovascular Medicine: Pursuing Cellular Longevity For Healthy Aging Is Intended To Offer Unique Insights Into The Cellular And Molecular Pathways That Can Govern Neuronal, Vascular, And Inflammatory Cell Function And Provide A Platform For Investigative Perspectives That Employ Novel Bench To Bedside Strategies From Internationally Recognized Scientific Leaders. In Light Of The Significant And Multifaceted Role Neuronal, Vascular, And Inflammatory Cells Play During Degenerative Disorders, Novel Studies That Elucidate The Role Of These Cells May Greatly Further Our Understanding Of Disease Mechanisms For The Development Of Targeted Treatments For A Wide Spectrum Of Diseases. The Authors Of This Monograph Strive To Lay The Course For The Continued Progression Of Innovative Investigations And Especially Those That Examine Previously Unexplored Pathways Of Cell Biology With New Avenues Of Study For The Maintenance Of Healthy Aging And Extended Cellular Longevity.

doody Review Services

reviewer:celso Agner, Md, Msc(university Of Illinois At Chicago College Of Medicine)
description:the Possible Relationship Between The Neurovascular System And Degenerative Diseases Has Long Been Explored. This Book Reviews The Topic And Supports The Idea With Current Scientific Evidence.
purpose:the Purpose Is To Attempt To Establish A Link Between The Neurovascular System And Degenerative Diseases Of The Central Nervous System.
audience:neurologists, Neuroscientists, And Neurosurgeons Are The Target Audience. The Authors Are Neuroscientists With Many Years' Experience In The Field.
features:over 60 Authors Contribute 22 Chapters In This Book. Starting From The Premise That There Is A Close Relationship Between The Neurovascular System And Degenerative Conditions Of The Central Nervous System, The Authors Discuss Basic Molecular Biology Principles And How They Apply To The Current Understanding Of Diseases Such As Parkinson's, Alzheimer's, And Other Demyelinating Conditions. Supported By Up-to-date Scientific Evidence, The Authors Present Theories On The Vascular Origin Of Alzheimer's Disease And The Possible Link Between Amyloid Angiopathy And Cerebral Hypoperfusion, Leading To Cognitive Impairment. After Discussion Of The Main Neurodegenerative Diseases, The Authors Conclude By Presenting Current And Future Therapeutic Options Such As Gene Therapy And Stem Cell Transplantation.
assessment:this Well Written, Well Referenced, And Well Illustrated Book Is Without Parallel. The Discussion Of The Interaction Between Clinical And Possible Surgical Options For Neurodegenerative Diseases, Along With The Lack Of Current Similar Books, Gives This A Special Position In The Field.

Role of prion protein during normal physiology and disease / Adriana Simon Coitinho and Glaucia N.M. Hajj Role of protein kinase C and related pathways in vascular smooth muscle contraction and hypertension / Xiaoying Qiao and Raouf A. Khalil Brain temperature regulation during normal neural function and neuropathology / Eugene A. Kiyatkin Retinal cellular metabolism and its regulation and control / Dao-Yi Yu ... [et al.] Crosstalk between the autonomic nervous system and the central nervous system: mechanistic and therapeutic considerations for neuronal, immune, vascular, and somatic based diseases / Fuad Lechin and Bertha van der Dijs Neurobiology of chronic pain / Min Zhuo Physiological effects and disease manifestations of performance enhancing androgenic-anabolic steroids, growth hormone, and insulin / Michael R. Graham ... [et al.] Mesenchymal stem cells and transdifferentiated neurons in crosstalk with the tissue microenvironment: implications for translational science / Katarzyna A. Trzaska ... [et al.] Motoneurons from human embryonic stem cells: present status and future strategies for their use in regenerative medicine / K.S.Sidhu Adult neurogenesis, neuroinflammation, and therapeutic potential of adult neural stem cells / Philippe Taupin Glutamatergic signaling in neurogenesis / Noritaka Nakamichi and Yukio Yoneda Neuroimmune interactions that operate in the development and progression of inflammatory demyelinating diseases: lessons from pathogenesis of multiple sclerosis / Enrico Fainardi and Massimiliano Castellazzi Brain inflammation and the neuronal fate: from neurogenesis to neurodegeneration / Maria Antonietta Ajmone-Cat, Emanuele Cacci, and Luisa Minghetti Immunomodulation in the nervous and vascular systems during inflammation and autoimmunity: the role of T regulatory cells / Kokona Chatzantoni and Athanasia Mouzaki Alzheimer's disease: is it caused by cerebrovascular dysfunction? / Christian Humpel Proteases in beta-amyloid metabolism: potential therapeutic targets against Alzheimer's disease / Noureddine Brakch and Mohamed Rholam Neurobiology of post-ischemic recuperation in the aged mammalian brain / Aurel Popa-Wagner ... [et al.] Protein misfolding, mitochondrial disturbances, and kynurenines in the pathogenesis of neurodegenerative disorders / Gabriella Gárdián ... [et al.] Redox signaling and vascular function / J. Will Langston, Magdalena L. Circu, and Tak Yee Aw Gene therapy toward clinical application in the cardiovascular field / Hironori Nakagami, Mariana Kiomy Osako, and Ryuichi Morishita Role of advanced glycation end products, oxidative stress, and inflammation in diabetic vascular complications / Sho-ichi Yamagishi, Takanori Matsui, Kazuo Nakamura Reducing oxidative stress and enhancing neurovascular longevity during diabetes mellitus / Kenneth Maiese, Zhao Zhong Chong, and Faqi Li. From the Publisher : Biomedical ethics is a burgeoning academic field with complex and far-reaching consequences. Whereas in Western secular bioethics this subject falls within larger ethical theories and applications (utilitarianism, deontology, teleology, and the like), Islamic biomedical ethics has yet to find its natural academic home in Islamic studies. In this pioneering work, Abdulaziz Sachedina-a scholar with life-long academic training in Islamic law-relates classic Muslim religious values to the new ethical challenges that arise from medical research and practice. He depends on Muslim legal theory, but then looks deeper than juridical practice to search for the underlying reasons that determine the rightness or wrongness of a particular action. Drawing on the work of diverse Muslim theologians, he outlines a form of moral reasoning that can derive and produce decisions that underscore the spirit of the Shari'a. These decisions, he argues, still leave room to revisit earlier decisions and formulate new ones, which in turn need not be understood as absolute or final. After laying out this methodology, he applies it to a series of ethical questions surrounding the human life-cycle from birth to death, including such issues as abortion, euthanasia, and organ donation. The implications of Sachedina's work are broad. His writing is unique in that it aims at conversing with Jewish and Christian ethics, moving beyond the Islamic fatwa literature to search for a common language of moral justification and legitimization among the followers of the Abrahamic traditions. He argues that Islamic theological ethics be organically connected with the legal tradition of Islam to enable it to sit in dialogue with secular and scripture-based bioethics in other faith communities. A breakthrough in Islamic bioethical studies, this volume is welcome and long-overdue reading for anyone interested in facing the difficult questions posed by modern medicine not only to the Muslim faithful but to the ethically-minded at large.

biomedical Ethics Is A Burgeoning Academic Field With Complex And Far-reaching Consequences. Whereas In Western Secular Bioethics This Subject Falls Within Larger Ethical Theories And Applications (utilitarianism, Deontology, Teleology, And The Like), Islamic Biomedical Ethics Has Yet To Find Its Natural Academic Home In Islamic Studies.

in This Pioneering Work, Abdulaziz Sachedina - A Scholar With Life-long Academic Training In Islamic Law - Relates Classic Muslim Religious Values To The New Ethical Challenges That Arise From Medical Research And Practice. He Depends On Muslim Legal Theory, But Then Looks Deeper Than Juridical Practice To Search For The Underlying Reasons That Determine The Rightness Or Wrongness Of A Particular Action. Drawing On The Work Of Diverse Muslim Theologians, He Outlines A Form Of Moral Reasoning That Can Derive And Produce Decisions That Underscore The Spirit Of The Shari'a. These Decisions, He Argues, Still Leave Room To Revisit Earlier Decisions And Formulate New Ones, Which In Turn Need Not Be Understood As Absolute Or Final. After Laying Out This Methodology, He Applies It To A Series Of Ethical Questions Surrounding The Human Life-cycle From Birth To Death, Including Such Issues As Abortion, Euthanasia, And Organ Donation.

the Implications Of Sachedina's Work Are Broad. His Writing Is Unique In That It Aims At Conversing With Jewish And Christian Ethics, Moving Beyond The Islamic Fatwa Literature To Search For A Common Language Of Moral Justification And Legitimization Among The Followers Of The Abrahamic Traditions. He Argues That Islamic Theological Ethics Be Organically Connected With The Legal Tradition Of Islam To Enable It To Sit In Dialogue With Secular And Scripture-based Bioethics In Other Faith Communities. A Breakthrough In Islamic Bioethical Studies, This Volume Is Welcome And Long-overdue Reading For Anyone Interested In Facing The Difficult Questions Posed By Modern Medicine Not Only To The Muslim Faithful But To The Ethically-minded At Large.

Disorders of the nervous and vascular systems continue to burden the planet's population not only with increasing morbidity and mortality, but also with a significant financial drain through increasing medical care costs coupled to a progressive loss in economic productivity. For example, more than 500 million individuals suffer from nervous and vascular system disorders in the world that comprise both acute and chronic degenerative diseases such as hypertension, cardiac insufficiency, diabetes mellitus, stroke, traumatic brain injury, and Alzheimer's disease. Given the vulnerability of the nervous and vascular systems, identifying the cellular pathways that determine cellular function, injury, and longevity may significantly assist in the development of therapeutic strategies to either prevent or at least reduce disability from crippling degenerative disorders. This book is intended to offer unique insights into the cellular and molecular pathways that can govern neuronal, vascular, and inflammatory cell function and provide a platform for investigative perspectives that employ novel “bench to bedside” strategies from internationally recognized scientific leaders. In light of the significant and multifaceted role played by neuronal, vascular, and inflammatory cells during degenerative disorders, novel studies that elucidate the role of these cells may greatly further our understanding of disease mechanisms for the development of targeted treatments for a wide spectrum of diseases. This book lays the course for the continued progression of innovative investigations and especially those that examine previously unexplored pathways of cell biology with new avenues of study for the maintenance of healthy aging and extended cellular longevity Neurovascular Medicine: Pursuing Cellular Longevity for Healthy Aging provides a unique perspective from a diverse group of international recognized investigators with a broad range of experience in neuronal, vascular, and immune mediated disease processes to translate previously unexplored pathways of cell biology into robust and safe therapeutic measures.