LC/MS : A Practical User's Guide

A practical guide to using and maintaining an LC/MS system The combination of liquid chromatography (LC) and mass spectrometry (MS) has become the laboratory tool of choice for a broad range of industries that require the separation, analysis, and purification of mixtures of organic compounds. LC/MS: A Practical User's Guide provides LC/MS users with an easy-to-use, hands-on reference that focuses on the practical applications of LC/MS and introduces the equipment and techniques needed to use LC/MS successfully. Following a thorough explanation of the basic components and operation of the LC/MS system, the author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer for any given problem. LC/MS covers everything users need to know about: The latest equipment, including quadrupole, time-of-flight, and ion trap analyzers Cutting-edge processes, such as preparing HPLC mobile phases and samples; handling and maintaining a wide variety of silica, zirconium, and polymeric separation columns; interpreting and quantifying mass spectral data; and using MS interfaces Current and future applications in the pharmaceutical and agrochemical industries, biotechnology, clinical research, environmental studies, and forensics An accompanying PowerPoint® slide-set on CD-ROM provides vital teaching tools for instructors and new equipment operators. Abundantly illustrated and easily accessible, the text is designed to help students and practitioners acquire optimum proficiency in this powerful and rapidly advancing analytical application.

a Practical Guide To Using And Maintaining An Lc/ms System

the Combination Of Liquid Chromatography (lc) And Mass Spectrometry (ms) Has Become The Laboratory Tool Of Choice For A Broad Range Of Industries That Require The Separation, Analysis, And Purification Of Mixtures Of Organic Compounds.

lc/ms: A Practical User's Guide Provides Lc/ms Users With An Easy-to-use, Hands-on Reference That Focuses On The Practical Applications Of Lc/ms And Introduces The Equipment And Techniques Needed To Use Lc/ms Successfully. Following A Thorough Explanation Of The Basic Components And Operation Of The Lc/ms System, The Author Presents Empirical Methods For Optimizing The Techniques, Maintaining The Instrumentation, And Choosing The Appropriate Ms Or Lc/ms Analyzer For Any Given Problem.

lc/ms Covers Everything Users Need To Know About:

• the Latest Equipment, Including Quadrupole, Time-of-flight, And Ion Trap Analyzers
• cutting-edge Processes, Such As Preparing Hplc Mobile Phases And Samples; Handling And Maintaining A Wide Variety Of Silica, Zirconium, And Polymeric Separation Columns; Interpreting And Quantifying Mass Spectral Data; And Using Ms Interfaces
• current And Future Applications In The Pharmaceutical And Agrochemical Industries, Biotechnology, Clinical Research, Environmental Studies, And Forensics

an Accompanying Powerpoint® Slide-set On Cd-rom Provides Vital Teaching Tools For Instructors And New Equipment Operators. Abundantly Illustrated And Easily Accessible, The Text Is Designed To Help Students And Practitioners Acquire Optimum Proficiency In This Powerful And Rapidly Advancing Analytical Application.

A practical guide to using and maintaining an LC/MS system The combination of liquid chromatography (LC) and mass spectrometry (MS) has become the laboratory tool of choice for a broad range of industries that require the separation, analysis, and purification of mixtures of organic compounds. LC/MS: A Practical User's Guide provides LC/MS users with an easy-to-use, hands-on reference that focuses on the practical applications of LC/MS and introduces the equipment and techniques needed to use LC/MS successfully. Following a thorough explanation of the basic components and operation of the LC/MS system, the author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer for any given problem. LC/MS covers everything users need to know about:Note: CD-ROM/DVD and other supplementary materials are not included.... Presents technical data in an easily understood format, explains how to keep LC/MS systems up and running, and shows how to interpret and quantitate the mass spectral data using proven spectral databases, without devolving into a university-style course curriculum. Takes a purely practical approach to using and maintaining LC/MS systems. Introduces the reader to quadrupole and ion trap analyzers, which make up the bulk of the equipment being sold for laboratory and analytical studies. Presents technical data in an illustrated, easily understood format. Explains how to keep systems up and running. Shows how to interpret and quantitate mass spectral data using proven spectral databases. [Ed.] "LC/MS: A Practical User's Guide provides LC/MS users with an easy-to-use, hands-on reference that focuses on the practical applications of LC/MS and introduces the equipment and techniques needed to use LC/MS successfully. Following a thorough explanation of the basic components and operation of the LC/MS system, the author presents empirical methods for optimizing the techniques, maintaining the instrumentation, and choosing the appropriate MS or LC/MS analyzer for any given problem."--Jacket fmatter......Page 1 ch1......Page 11 ch2......Page 19 ch3......Page 31 ch4......Page 43 ch5......Page 51 ch6......Page 60 ch7......Page 67 ch8......Page 78 ch9......Page 92 ch10......Page 101 ch11......Page 108 ch12......Page 115 ch13......Page 123 ch14......Page 130 app1......Page 134 app2......Page 142 app3......Page 146 app4......Page 152 app5......Page 158 index......Page 160