Mass spectrometry basics -

Boca Raton, London, New York, Washington, D.C. CRC Press, Taylor & Francis Group, LLC, 2003. – 474 p. This book began as a small series of brief articles designed to assist engineers and salesmen in understanding some aspects of ion chemistry and mass spectrometry. Each article was composed of a very short summary and a longer section that described aspects of the subject matter in somewhat greater detail. To facilitate rapid reading and assimilation, extensive use was made of figures and tables, which contain additional information in their legends or footnotes. From the outset of writing these articles, it was never intended that they should be exhaustively comprehensive, because this approach would have defeated the aims of the whole exercise, viz. , the provision of short, quick explanations of major elements of mass spectrometry and closely allied topics. The traditional, more all-embracing approach to writing about mass spectrometry was left to the many excellent authors, who have provided impressive textbooks. In contrast, the major objective of the Back-to-Basics series was the provision of quick explanations of fundamental concepts in mass spectrometry, without overelaboration. As far as possible, descriptions of processes, applications, and underlying science were made with a minimum of text backed up by easily and rapidly understood pictures. Although some major equations of relevance to mass spectrometry have been introduced, the mathematical derivations of these equations were largely omitted. This was not an attempt to dumb down an important discipline. Rather, the intent was to make some of the esoteric aspects of an important area of analysis readily comprehensible to the many people who have to deal with mass spectrometers but who have not been trained specifically in this branch of science and engineering. The series began about ten years ago and encompasses recent and past developments in mass spectrometry. However, since it is the principles of mass spectrometry that are explained and not specific instrumentation, the information content remains as relevant now as it was ten years ago. Mass Spectrometry Basics Is A Pedagogy For Novice Practitioners And Those With Little Or No Experience In The Field Of Mass Spectrometry. It Includes Information On Ionisation Processes, Techniques, Instruments, And General Ms And Combined Ms Applications. The Text Also Has An Extensive Reference Section And Quick Guides That Highlight The Essential Information Discussed In Each Chapter. Chemical Ionization (ci) -- Laser Desorption Ionization (ldi) -- Electron Ionization (ei) -- Fast-atom Bombardment (fab) And Liquid-phase Secondary Ion Mass Spectrometry (lsims) Ionization -- Field Ionization (fi) And Field Desorption (fd) -- Coronas, Plasmas, And Arcs -- Thermal Ionization (ti), Surface Emission Of Ions -- Electrospray Ionization (esi) -- Atmospheric-pressure Ionization (api) -- Z-spray Combined Inlet/ion Source -- Thermospray And Plasmaspray Interfaces -- Particle-beam Interface -- Dynamic Fast-atom Bombardment And Liquid-phase Secondary Ion Mass Spectrometry (fab/lsims) Interface -- Plasma Torches -- Sample Inlets For Plasma Torches, Part A : Gases -- Sample Inlets For Plasma Torches, Part B : Liquid Inlets -- Sample Inlets For Plasma Torches, Part C : Solid Inlets -- Lasers And Other Light Sources -- Nebulizers -- Hybrid Orthogonal Time-of-flight (oa-tof) Instruments -- Hybrid Magnetic-sector Time-of-flight (sector/tof) Instruments --^ Hybrid Hexapole Time-of-flight (hexapole/tof) Instruments -- Hybrid Quadrupole Time-of-flight (q/tof) Instruments -- Ion Optics Of Magnetic/electric-sector Mass Spectrometers -- Quadrupole Ion Optics -- Time-of-flight (tof) Ion Optics --orthogonal Time-of-flight (oa-tof) Ion Optics -- Point Ion Collectors (detectors) -- Array Collectors (detectors) -- Comparison Of Multipoint Collectors (detectors) Of Ions : Arrays And Microchannel Plates -- Time-to-digital Converters (tdc) -- Origin And Uses Of Metastable Ions -- Linked Scanning And Metastable Ions In Quadrupole Mass Spectrometry -- Linked Scanning And Metastable Ions In Magnetic-sector Mass Spectrometry -- Gas Chromatography (gc) And Liquid Chromatography (lc) -- Gas Chromatography/mass Spectrometry (gc/ms) -- Liquid Chromatography/mass Spectrometry (lc/ms) --high-resolution, Accurate Mass Measurement : Elemental Compostions -- Choice Of Mass Spectrometer -- Analysis Of Peptides And Proteins By Mass Spectrometry --^ Environmental Protection Agency Protocols -- Computers And Transputers In Mass Spectrometers, Part A. -- Computers And Transputers In Mass Spcetometers, Part B -- Computers And Transputers In Mass Spectrometers, Part C -- Introduction To Biotechnology -- Isotopes And Mass Spectrometry -- Uses Of Isotope Ratios -- Variations In Isotope Ratios -- Transmission Of Ions Through Inhomogenous Rf Fields. Christopher G. Herbert, Robert A.w. Johnstone. Compilation Of Articles Previously Published In The Series Back-to-basics. Includes Bibliographical References (p. 449-452) And Index. Mass Spectrometry Basics provides authoritative yet plain-spoken explanations of the basic concepts of this powerful analytical method without elaborate mathematical derivations. The authors describe processes, applications, and the underlying science in a concise manner supported by figures and graphics to further comprehension. The text provides practical approaches to interpreting mass spectral data and step-by-step guides for identifying chemically relevant compounds. Additionally, the authors have included an extensive reference section and a quick guide to each chapter that offers immediate access to key information. This unique reference makes some of the esoteric aspects of this important area of analysis more readily comprehensible to those who deal with analytical instruments but who have not been trained in mass spectrometry. It also serves as a refresher for practicing mass spectroscopists by clarifying principles to afford a better appreciation and application of this technology. Offers explanations of the basic concepts of the analytical method - mass spectrometry. This book describes processes, applications, and the underlying science supported by figures and graphics that further readers' comprehension. This chapter should be read in conjunction with Chapter 3, "Electron Ionization."