Mobile Genetic Elements

Mobile Genetic Elements introduces the nonspecialist to the biology and genetics of mobile elements. It attempts to make the biochemistry of DNA rearrangements more accessible to embryologists and evolutionists, and to illuminate the related developmental cycles to the biochemist. The book also shows how natural the activity of mobile elements can be in diverse biological situations. The chapters describe several well-studied cases in which genetic determinants—often identified as specific nucleic acid sequences—repeatedly change their positions within or between cellular genomes. Because their genomic positions are not fixed, these determinants may conveniently be classed together under the rubric of mobile genetic elements. The book begins with a discussion of maize controlling elements. This is followed by separate chapters on the bacteriophages? and Mu; nonviral mobile elements in bacteria; transposable Ty elements in brewer's yeast; Drosophila transposable element; and hybrid dysgenesis. Subsequent chapters cover vertebrate retroviruses; Agrobacterium oncogenesis in plants; flagellar phase variation in Salmonella; yeast mating type; and surface antigenic variation in trypanosomes. Content: Front Matter , Page iii Copyright , Page iv Contributors , Pages ix-x Genomic Reorganization in Cell Lineages , Pages xi-xvi , JAMES A. SHAPIRO CHAPTER 1 - Controlling Elements in Maize , Pages 1-12,12a,12b,13-63 , NINA V. FEDOROFF CHAPTER 2 - Bacteriophage λ , Pages 65-103 , ALLAN CAMPBELL CHAPTER 3 - Phage Mu: Transposition as a Life-Style , Pages 105-158 , ARIANE TOUSSAINT, ANNE RÉSIBOIS CHAPTER 4 - Prokaryotic IS Elements , Pages 159-221 , SHIGERU IIDA, JÜRG MEYER, WERNER ARBER CHAPTER 5 - Tn 3 and Its Relatives , Pages 223-260 , FRED HEFFRON CHAPTER 6 - Transposon Tn 10 , Pages 261-298 , NANCY KLECKNER CHAPTER 7 - Transposable Elements in Yeast , Pages 299-328 , G. SHIRLEEN ROEDER, GERALD R. FINK CHAPTER 8 - Dispersed Repetitive DNAs in Drosophila , Pages 329-361 , GERALD M. RUBIN CHAPTER 9 - Hybrid Dysgenesis Determinants , Pages 363-410 , JEAN-CLAUDE BREGLIANO, MARGARET G. KIDWELL CHAPTER 10 - Retroviruses , Pages 411-503 , HAROLD E. VARMUS CHAPTER 11 - Agrobacterium Tumor Induction , Pages 505-535 , PATRICIA ZAMBRYSKI, HOWARD M. GOODMAN, MARC VAN MONTAGU, JEFF SCHELL CHAPTER 12 - Phase Variation and Related Systems , Pages 537-557 , MICHAEL SILVERMAN, MELVIN SIMON CHAPTER 13 - Mating-Type Genes of Saccharomyces cerevisiae , Pages 559-619 , JAMES E. HABER CHAPTER 14 - Antigenic Variation in Trypanosomes , Pages 621-659 , P. BORST Index , Pages 661-688