Pharmaceutical Dosage Forms - Capsules

**__Pharmaceutical Dosage Forms: Capsules__** covers the development, composition, and manufacture of capsules. Despite the important role that capsules play in drug delivery and product development, few comprehensive texts on the science and technology of capsules have been available for the research and academic environments. This text addresses this gap, discussing how capsules provide unique capabilities and options for dosage form design and formulation. Content: Advances in capsule formulation and filling / Larry L. Augsburger and Stephen W. Hoag -- An introduction to two-piece hard capsules and their marketing benefits / Dennis Murachanian -- Hard shell capsules in clinical trials / Moji Christianah Adeyeye and Amusa Adebayo -- Manufacture of capsule shells / Brian E. Jones, Fridrun Podczeck and Paul Lukas -- Non-gelatin based capsules / Sven Stegemann -- Hard shell capsule filling machines / Donald K. Lightfoot -- Instrumented capsule filling machines and filling machine simulators / Vikas Moolchandani and Larry L. Augsburger -- Dry-fill formulation and filling technology / Pavan Heda, Vikas Agarwal and Shailesh K. Singh -- Plug formation / Fridrun Podczeck and Brian E. Jones -- Modeling powder filling during encapsulation / Ammar Khawam -- Scaling-up and transfer of hard shell formulations across machine types / Larry L. Augsburger and Michael Levin -- Modified release delivery systems : extended release capsule platform / Reza Fassihi -- Analytical testing and evaluation of capsules / Stuart L. Cantor and Asis K. Dutta -- Rheological aspects of capsule shell excipients and the manufacture of encapsulated formulations / Lawrence H. Block -- Quality-by-design (QBD) for capsule formulation and process development : regulatory science developments, scientific case studies, and future challenges / Huiquan Wu, Lin Xie, Stephen W. Hoag, Larry L. Augsburger, Mansoor Khan.