Primary Hematology (Current Clinical Practice Series)

The discipline of hematology ranges widely from the diagnosis and management of anemia to hematologic malignancies and transfusion medicine, and involves significant ethical issues and problems in statistical interpretation. In Primary Hematology, Ayalew Tefferi, MD, and a team of authoritative practicing physicians concisely detail their most effective approaches to the diagnosis and treatment of a wide variety of hematological disorders, including anemia and other cytopenias, primary and secondary myeloproliferative disorders, lymphoid and plasma cell disorders, and thrombotic and bleeding disorders. For each illness these expert clinicians provide a brief review of basic concepts and a discussion of its symptomology and classification, its diagnostic tests, and strategies for its management, along with suggested readings for more detailed information. Numerous decision trees clarify diagnosis, and summary boxes highlight key points and dosage parameters. Other areas covered include leukemias and hematopoietic stem cell transplantation, transfusion medicine, hereditary hemochromatosis, the hematologic manifestations of HIV disease, porphyria, and the use of hematopoietc growth factors in clinical practice. Concise, practical, and up-to-date, Primary Hematology offers busy primary care physicians, internists, hematologists, and oncologists a much-needed action-oriented summary of proven approaches to the optimal diagnosis and treatment of hematologic disorders today. Doody Review Services Reviewer: Lisa Boggio, MS, MD(Northwestern University Feinberg School of Medicine) Description: Hematology often can be a confusing subject. Articles and book chapters about disease conditions are very long and often not filled with practical information needed to treat patients. Now there is a primer of hematology. Each chapter has concise descriptions of each disease and its pathogenesis in the form of concise text supplemented by many figures and tables. This provides not only complete descriptions of the diseases, but makes a great reference. Purpose: The purpose, to provide clinicians of many disciplines an understanding of common and uncommon problems of hematology, is achieved. Audience: Although it is written for practicing clinicians -- hematologists, cardiologists, neurologists, and internists -- others would also benefit from its information. Medical students and nurses would also find it helpful. Features: The anemias, thrombosis, malignancies, porphyria, and ethics are all covered in a thorough, yet easy to read manner. The sections about porphyria are excellent and the author was able to make an often confusing topic very easy to understand and to put into practical use. There is no paucity of figures. Each adds to the understanding of the topic. Especially notable are the figures in the myeloproliferative disease section written by the editor. They not only add to understanding the topic, but are important examples of disease that should not go unrecognized by the clinician. An example is the figure showing retinal vein distension in polycythemia vera (Figure 3, Plate 10). Assessment: This book gives easy-to-read, in-depth descriptions of various common and uncommon problems encountered in hematology. The tables and figures enhance, but do not rehash, what is in the text. This is an excellent reference for physicians, nurses, and students. Front Matter....Pages i-xiv Front Matter....Pages 1-1 A Practical Approach to the Diagnosis of Anemia....Pages 3-20 Specific Anemia Syndromes and Their Management....Pages 21-40 The Thalassemia Syndromes and the Hemoglobinopathies....Pages 41-64 Sickle Cell Disorders....Pages 65-82 Practical Aspects in the Diagnosis and Management of Aplastic Anemia....Pages 83-91 Differential Diagnosis of Neutropenia....Pages 93-104 Causes and Management of Isolated Thrombocytopenia....Pages 105-115 Front Matter....Pages 117-117 An Approach to the Patient With Erythrocytosis....Pages 119-128 Differential Diagnosis and Management of Thrombocytosis....Pages 129-135 Chronic Myeloproliferative Diseases: Polycythemia Vera and Agnogenic Myeloid Metaplasia....Pages 137-147 An Approach to the Patient With Myelodysplasia....Pages 149-159 The Eosinophil and Eosinophilia....Pages 161-171 Front Matter....Pages 173-173 Leukocytosis and the Chronic Leukemias....Pages 175-192 Acute Leukemia....Pages 193-208 Blood and Marrow Transplantation....Pages 209-227 Front Matter....Pages 229-229 Lymphadenopathy....Pages 231-239 Hodgkin’s Disease and Non-Hodgkin’s Lymphoma....Pages 241-253 An Evaluation of Patients With Monoclonal Gammopathies....Pages 255-267 Multiple Myeloma and Related Disorders....Pages 269-288 Front Matter....Pages 289-289 An Overview of the Hemostatic System and Interpretation of Common Screening Coagulation Tests....Pages 291-302 Front Matter....Pages 289-289 Bleeding Disorders: An Overview and Clinical Practice....Pages 303-316 Thrombogenesis and Thrombotic Disorders....Pages 317-335 Front Matter....Pages 337-337 Transfusion Medicine: Practical Issues....Pages 339-349 Hereditary Hemochromatosis: A Disease for All Physicians....Pages 351-364 Hematologic Manifestations of HIV Disease....Pages 365-370 Hematopoietic Growth Factors in Clinical Practice....Pages 371-377 A Primer of Chemotherapy....Pages 379-406 An Approach to Porphyria....Pages 407-414 Ethical Issues in the Care of Patients With Hematologic Diseases....Pages 415-430 Statistical Methods Frequently Used in Hematology Research....Pages 431-450 Back Matter....Pages 451-472 Provides approaches to the optimal diagnosis and treatment of hematologic disorders, including anemia and other cytopenias, primary and secondary myeloproliferative disorders, lymphoid and plasma cell disorders, and thrombotic and bleeding disorders. This title is suitable for primary care physicians, internists, hematologists, and oncologists.