Stem Cell and Tissue Engineering

Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. A challenge for tissue engineering is to identify appropriate cell sources. The recent advancement of stem cell biology provides enormous opportunities to engineer stem cells for tissue engineering. The impact of stem cell technology on tissue engineering will be revolutionary. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It serves as a valuable reference book for researchers and students Book jacket Tissue engineering: from basic biology to cell-based applications / Robert M. Nerem Recent advances and future perspectives on somatic cell reprogramming / Kun-Yong Kim and In-Hyun Park Hematopietic stem cells / Jennifer J. Trowbridege Mesenchymal stem cells for tissue regeneration / Ngana F. Huang and Song Li Delivery vehicles for deploying mesenchymal stem cells in tissue repair / Michael S. Friedman and J. Kent Leach Stem cells for cardiac tissue engineering / Jennifer L. Young, Karen L. Christman and Adam J. Engler Cardiovascular system: stem cells in tissue-engineered blood vessels / Rajendra Sawh-Martinez ... [et al.] Stem cells for vascular regeneration: an engineering approach / Laura E. Dickinson and Sharon Gerecht Stem cells and wound repair / Sae Hee Ko ... [et al.] Engineering cartilage: from materials to small molecules / Jeannine M. Coburn and Jennifer H. Elisseeff ^ Adult stem cells for articular cartilage tissue engineering / Sushmita Saha ... [et al.] Stem cells for disc repair / Aliza A. Allon ... [et al.] Skeletal tissue engineering: progress and prospects / Nicholas J. Panetta, Deepak M. Gupta and Michael T. Longaker Clinical applications of a stem cell based therapy for oral bone reconstruction / Bradley McAllister and Kamran Haghighat Therapeutic strategies for repairing the injured spinal cord using stem cells / Michael S. Beattie and Jacqueline C. Bresnahan Potential of tissue engineering and neural stem cells in the understanding and treatment of neurodegenerative diseases / Caroline Auclair-Daigle and François Berthod High-throughput systems for stem cell engineering / David A. Brafman, Karl Willert and Shu Chien Microscale technologies for tissue engineering and stem cell differentiation / Jason W. Nichol ... [et al.] ^ ^^ Quality control of autologous cell-and tissue-based therapies / Nathalie Dusserre, Todd McAllister and Nicholas L'Heureux Regulatory challenges for cell-based therapeutics / Todd McAllister ... [et al.]. ^^ World Scientific Front Cover 1 Title Page 2 Copyright 4 Contents 6 Contributors 14 Preface 24 1. Tissue Engineering: From Basic Biology to Cell-Based Applications 26 2. Recent Advances and Future Perspectives on Somatic Cell Reprogramming 38 3. Hematopoietic Stem Cells 56 4. Mesenchymal Stem Cells for Tissue Regeneration 74 5. Delivery Vehicles for Deploying Mesenchymal Stem Cells in Tissue Repair 96 6. Stem Cells for Cardiac Tissue Engineering 120 7. Cardiovascular System: Stem Cells in Tissue-Engineered Blood Vessels 140 8. Stem Cells for Vascular Regeneration: An Engineering Approach 160 9. Stem Cells and Wound Repair 184 10. Engineering Cartilage: From Materials to Small Molecules 206 11. Adult Stem Cells for Articular Cartilage Tissue Engineering 236 12. Stem Cells for Disc Repair 256 13. Skeletal Tissue Engineering: Progress and Prospects 276 14. Clinical Applications of a Stem Cell Based Therapy for Oral Bone Reconstruction 302 15. Therapeutic Strategies for Repairing the Injured Spinal Cord Using Stem Cells 322 16. Potential of Tissue Engineering and Neural Stem Cells in the Understanding and Treatment of Neurodegenerative Diseases 346 17. High-Throughput Systems for Stem Cell Engineering 372 18. Microscale Technologies for Tissue Engineering and Stem Cell Differentiation 400 19. Quality Control of Autologous Celland Tissue-Based Therapies 422 20. Regulatory Challenges for Cell-Based Therapeutics 448 Index 466 ISBN-13:,9789814317054 ISBN-13: 9789814317054 Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. This book covers knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells. It is suitable for researchers and students. Annotation Tissue engineering integrates knowledge and tools from biological sciences and engineering for tissue regeneration. This book covers state-of-the-art knowledge on the potential of stem cells for the regeneration of a wide range of tissues and organs and the technologies for studying and engineering stem cells