The Case-Control Study: Consensus and Controversy focuses on the history and the evolution of the case-control study, addresses the methodological issues discussed in this book, and presents illustrative studies to examine the problems and opportunities inherent in the method. This text first discusses the progress and evolution of case-control studies. This book then explains methodologic problems and standards in case-control research, which is followed by a discussion on bias in analytic research. Before this book gives the highlights of the conference it documents, it first tackles the confidence intervals for the odds ratio in case-control studies; case-control studies on the effect of sex steroids on women and their offspring; and methodologic variation in case-control studies of reserpine and breast cancer. This text also looks into the questions frequently asked regarding case-control studies, such as on the selection of appropriate controls, publication of research findings, and type of research needs to be done on case-control studies to improve them. This book concludes by explaining the development of standards for case control studies, as well as other problems and prospect regarding this study. This publication will be invaluable to those interested in case-control studies. Content: Front Matter, Page i Copyright, Page ii PREFACE, Page 1, WALTER O. SPITZER LIST OF PARTICIPANTS, Pages 3-4 A CENTURY OF CASE-CONTROL STUDIES: PROGRESS?, Pages 5-13, ABRAHAM M. LILIENFELD, DAVID E. LILIENFELD COMMENT, Page 14, CAROL BUCK THE EVOLVING CASE-CONTROL STUDY, Pages 15-27, PHILIP COLE COMMENT, Pages 28-29, E.D. ACHESON DISCUSSION FOLLOWING Drs. COLE AND ACHESON, Pages 30-34 METHODOLOGIC PROBLEMS AND STANDARDS IN CASE-CONTROL RESEARCH, Pages 35-41, ALVAN R. FEINSTEIN COMMENT, Pages 42-44, PHILIP E. SARTWELL DISCUSSION FOLLOWING Drs. FEINSTEIN AND SARTWELL, Pages 45-49 BIAS IN ANALYTIC RESEARCH, Pages 51-63, David L. Sackett COMMENT, Pages 64-66, M.P. VESSEY DISCUSSION FOLLOWING Drs. SACKETT AND VESSEY, Pages 67-68 CONFIDENCE INTERVALS FOR THE ODDS RATIO IN CASE-CONTROL STUDIES: THE STATE OF THE ART, Pages 69-77, JOSEPH L. FLEISS COMMENT, Pages 78-79, DAVID J. FINNEY COMMENT, Pages 80-82, OLLI MIETTINEN CASE-CONTROL STUDIES ON THE EFFECT OF SEX STEROIDS ON WOMEN AND THEIR OFFSPRING, Pages 83-88, DWIGHT T. JANERICH, DONNA GLEBATIS, ELLEN FLINK, MARGARET B. HOFF COMMENT, Pages 89-90, W.H.W. INMAN DISCUSSION FOLLOWING Drs. JANERICH AND INMAN, Pages 91-94 METHODOLOGIC VARIATION IN CASE-CONTROL STUDIES OF RESERPINE AND BREAST CANCER, Pages 95-104, DARWIN R. LABARTHE COMMENT, Pages 105-107, S. SHAPIRO, D. SLONE DISCUSSION FOLLOWING Drs. LABARTHE AND SHAPIRO, Pages 108-113 HIGHLIGHTS OF CONFERENCE, Pages 115-116, PAUL STOLLEY FINAL DISCUSSION, Pages 117-137, ALL PARTICIPANTS THE CASE CONTROL STUDY: THE PROBLEM AND THE PROSPECT, Pages 139-144, MICHEL A. IBRAHIM, WALTER O. SPITZER Selected Annotated Bibliography of Case-Control Studies, Pages 145i,145ii,145iii,145iv, Ralph I. Horwitz SUBJECT INDEX, Pages 149v,149vi,149vii,149viii
