The Circulating Platelet

The Circulating Platelet focuses on the biochemistry and physiology of platelets. Composed of contributions of authors, the compilation starts with the discussions on the origin, discovery, production, and life span of blood platelets. The discussions continue with the morphology of platelets. Concerns include peripheral, sol-gel, and organelle zones and the membrane systems. The book also looks at the energy metabolism of thrombocytes and highlights the presence of glycoproteins in blood platelets. These include polysaccharides, glucosaminoglycans, and glycoproteins. The text also discusses the properties, functions, and the physiological value of thrombosthenin. The compilation further discusses platelet aggregation and functions of platelets. Concerns include collection and processing of platelets; preparation of homogenates; and the agents that influence platelet aggregation. The role of platelets in blood clots and fibrinolysis is emphasized. The selection ends with discussions on the immunological reactions of platelets; the clinical diseases related to blood platelets; and blood transfusion and preservation. The text is vital for researchers interested in studying blood platelets. Content: CONTRIBUTORS , Page ii Front Matter , Page iii Copyright , Page iv Dedication , Pages x-xiv , WALTER H. SEEGERS LIST OF CONTRIBUTORS , Pages xv-xvi PREFACE , Page xvii , SHIRLEY A. JOHNSON 1 - HISTORICAL PERSPECTIVES AND THE BLOOD PLATELETS , Pages 1-18 , JOHN W. REBUCK 2 - ORIGIN, PRODUCTION, AND LIFE-SPAN OF BLOOD PLATELETS , Pages 19-43 , SHIRLEY EBBE 3 - PLATELET MORPHOLOGY , Pages 45-121 , JAMES G. WHITE 4 - ENERGY METABOLISM , Pages 123-188 , RUDOLF GROSS, WOLFGANG SCHNEIDER 5 - MEMBRANE GLYCOPROTEINS OF BLOOD PLATELETS , Pages 189-205 , G.A. JAMIESON, D.S. PEPPER 6 - PLATELET PROTEINS , Pages 207-224 , RALPH L. NACHMAN 7 - THROMBOSTHENIN , Pages 225-239 , ERNST F. LÜSCHER, M. BETTEX-GALLAND 8 - FUNCTIONS OF PLATELET MEMBRANES , Pages 241-258 , AARON J. MARCUS, LENORE B. SAFIER, HARRIS L. ULLMAN 9 - PLATELET AGGREGATION , Pages 259-281 , LOUIS M. ALEDORT 10 - ENDOTHELIAL SUPPORTING FUNCTION OF PLATELETS , Pages 283-299 , SHIRLEY A. JOHNSON 11 - ROLE OF PLATELETS IN BLOOD CLOTTING , Pages 301-354 , WALTER H. SEEGERS 12 - PLATELETS IN HEMOSTASIS AND THROMBOSIS , Pages 355-393 , SHIRLEY A. JOHNSON 13 - ROLE OF PLATELETS IN FIBRINOLYSIS , Pages 395-413 , HAU.C. KWAAN 14 - IMMUNOLOGICAL REACTIONS INVOLVING PLATELETS , Pages 415-471 , ROGER M. DES PREZ, SAMUEL R. MARNEY Jr. 15 - CLINICAL DISORDERS RELATED TO BLOOD PLATELETS , Pages 473-539 , E.J. WALTER BOWIE, CHARLES A. OWEN JR. 16 - TRANSFUSION AND PRESERVATION , Pages 541-563 , SEYMOUR PERRY, RONALD A. YANKEE AUTHOR INDEX , Pages 565-591 SUBJECT INDEX , Pages 592-601