Understanding NMR Spectroscopy James Keeler Department of Chemistry, University of Cambridge, UK This text discusses the high-resolution NMR of liquid samples and concentrates exclusively on spin-half nuclei (mainly 1H and 13C). It is aimed at people who are familiar with the use of routine NMR for structure determination and who wish to deepen their understanding of just exactly how NMR experiments work. It demonstrates that in NMR it is possible, quite literally on the back of an envelope, to make exact predictions of the outcome of quite sophisticated experiments. The experiments chosen are likely to be encountered in the routine NMR of small to medium-sized molecules, but are also applicable to the study of large biomolecules, such as proteins and nucleic acids. The book starts off at a gentle pace, working through some more-or-less familiar ideas, and then elaborating these as the book progresses. Each chapter ends with exercises which are designed to assist in the understanding of the ideas presented and to grasp the underlying ideas. This Text Is Aimed At People Who Have Some Familiarity With High-resolution Nmr, And Who Now Wish To Deepen Their Understanding Of How Nmr Experiments Actually 'work'. The Book Concentrates On Those Experiments Which Are Commonly Used In Structural Studies Of Small- To Medium-sized Molecules. Although The Special Experiments Used In Biomolecular Nmr Are Not Considered Explicitly, The Key Concepts And Ideas Introduced In This Book Are Very Relevant To Understanding Such Experiments.--jacket. What This Book Is About And Who Should Read It -- Setting The Scene -- Energy Levels And Nmr Spectra -- The Vector Model -- Fourier Transformation And Data Processing -- The Quantum Mechanics Of One Spin -- Product Operators -- Two-dimensional Nmr -- Relaxation And The Noe -- Advanced Topics In Two-dimensional Nmr -- Coherence Selection -- How The Spectrometer Works. James Keeler. Includes Bibliographical References And Index. 1 What this course is about......Page 4 2 NMR and energy levels......Page 7 3 The vector model......Page 26 4 Fourier transformation and data processing......Page 48 5 How the spectrometer works......Page 66 6 Product Operators......Page 80 7 Two-dimensional NMR......Page 96 8 Relaxation......Page 126 9 Coherence Selection:Phase Cycling and Gradient Pulses......Page 151 Exercises for Chapters 6, 7, 8 & 9......Page 200 Concentrating on spin-half nuclei (mainly 1H and 13C), this text discusses the high-resolution NMR of liquid samples. It is aimed at people who are familiar with the use of routine NMR for structure determination, demonstrates that in NMR it is possible to make exact predictions of the outcome of sophisticated experiments
