Calmodulin and Signal Transduction

This book focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. Highlights: * Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes * Selected case studies and precedents related to molecular mechanisms * Protein-protein recognition between calmodulin and the enzymes it regulates * Cross-talk and interdigitation with other signal transduction pathways. Read more... Content: Front Matter , Page iii Copyright , Page iv Contributors , Pages ix-x Preface , Pages xi-xiv , Linda J. Van Eldik, D. Martin Watterson 1 - Calmodulin and Calcium Signal Transduction: An Introduction , Pages 1-15 , LINDA J. VAN ELDIK, D. MARTIN WATTERSON 2 - Calmodulin as a Calcium Sensor , Pages 17-64 , MELANIE R. NELSON, WALTER J. CHAZIN 3 - Calmodulin-Regulated Protein Kinases , Pages 65-168 , THOMAS J. LUKAS, SALIDA MIRZOEVA, D. MARTIN WATTERSON 4 - Biochemistry and Pharmacology of Calmodulin-Regulated Phosphatase Calcineurin , Pages 169-236 , BRIAN A. PERRINO, THOMAS R. SODERLING 5 - Cyclic Nucleotide Regulation by Calmodulin , Pages 237-286 , WILLIAM K. SONNENBURG, GARY A. WAYMAN, DANIEL R. STORM, JOSEPH A. BEAVO 6 - Regulation of Nitric Oxide Synthase by Calmodulin , Pages 287-345 , JINGRU HU, LINDA J. VAN ELDIK 7 - Calmodulin-Binding Proteins of the Cytoskeleton , Pages 347-396 , NATHALIE M. BONAFÉ, JAMES R. SELLERS 8 - Calmodulin and Ion Flux Regulation , Pages 397-471 , PAUL C. BRANDT, THOMAS C. VANAMAN Index , Pages 473-482 This book focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways.

Highlights:
* Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes
* Selected case studies and precedents related to molecular mechanisms
* Protein-protein recognition between calmodulin and the enzymes it regulates
* Cross-talk and interdigitation with other signal transduction pathways Calmodulin and Signal Transduction focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways. It provides the reader with selected examples and experimental precedents that underlie current models of cell regulation through calmodulin-regulated pathways and their linkage with other regulatory pathways. Molecular mechanisms of calcium signal transduction through calmodulin-regulated enzymes Selected case studies and precedents related to molecular mechanisms Protein-protein recognition between calmodulin and the enzymes it regulates Cross-talk and interdigitation with other signal transduction pathways Providing readers with selected examples and experimental precedents, this volume focuses on emerging themes in the molecular mechanisms of calcium signal transduction through calmodulin-regulated pathways