DNA Nanotechnology : From Structure to Functionality

The series __Topics in Current Chemistry Collections__ presents critical reviews from the journal __Topics in Current Chemistry__ organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials" is available open access under a CC BY 4.0 License via link.springer.com. Front Matter ....Pages i-ix Towards active self-assembly through DNA nanotechnology (Jinyi Dong, Chao Zhou, Qiangbin Wang)....Pages 1-25 Tailoring DNA self-assembly to build hydrogels (Jie Chen, Ying Zhu, Huajie Liu, Lihua Wang)....Pages 27-56 DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials (Xuemei Xu, Pia Winterwerber, David Ng, Yuzhou Wu)....Pages 57-81 Engineering Functional DNA-Protein Conjugates for Biosensing, Biomedical, and Nanoassembly Applications (Dan Zhao, Yuhan Kong, Sisi Zhao, Hang Xing)....Pages 83-124 DNA-Scaffolded Proximity Assembly and Confinement of Multienzyme Reactions (Jinglin Fu, Zhicheng Wang, Xiao Hua Liang, Sung Won Oh, Ezry St. Iago-McRae, Ting Zhang)....Pages 125-155 Directional assembly of nanoparticles by DNA shapes: towards designed architectures and functionality (Ningning Ma, Brian Minevich, Jiliang Liu, Min Ji, Ye Tian, Oleg Gang)....Pages 157-190 Oligonucleotide-Polymer Conjugates: From Molecular Basic to Practical Application (Fan Xiao, Zixiang Wei, Maggie Wang, Alexandra Hoff, Ying Bao, Leilei Tian)....Pages 191-233 Biotechnological and Therapeutic Applications of Natural Nucleic Acid Structural Motifs (Jinwei Duan, Xing Wang, Megan E. Kizer)....Pages 235-266 DNA-driven Nanoparticle Assemblies for Biosensing and Bioimaging (Yuan Zhao, Lixia Shi, Hua Kuang, Chuanlai Xu)....Pages 267-299 Aptamer-functionalized DNA Nanostructures for Biological Applications (Xiaoyi Fu, Fangqi Peng, Jungyeon Lee, Qi Yang, Fei Zhang, Mengyi Xiong et al.)....Pages 301-343 High-performance biosensing based on autonomous enzyme-free DNA circuits (Hong Wang, Huimin Wang, Itamar Willner, Fuan Wang)....Pages 345-376 DNA strand displacement reaction: a powerful tool for discriminating single nucleotide variants (Weiyang Tang, Weiye Zhong, Yun Tan, Guan A. Wang, Feng Li, Yizhen Liu)....Pages 377-406 "The series Topics in Current Chemistry Collections presents critical reviews from the journal Topics in Current Chemistry organized in topical volumes. The scope of coverage is all areas of chemical science including the interfaces with related disciplines such as biology, medicine and materials science. The goal of each thematic volume is to give the non-specialist reader, whether in academia or industry, a comprehensive insight into an area where new research is emerging which is of interest to a larger scientific audience. Each review within the volume critically surveys one aspect of that topic and places it within the context of the volume as a whole. The most significant developments of the last 5 to 10 years are presented using selected examples to illustrate the principles discussed. The coverage is not intended to be an exhaustive summary of the field or include large quantities of data, but should rather be conceptual, concentrating on the methodological thinking that will allow the non-specialist reader to understand the information presented. Contributions also offer an outlook on potential future developments in the field. The chapter "DNA-Programmed Chemical Synthesis of Polymers and Inorganic Nanomaterials" is available open access under a CC BY 4.0 License via link.springer.com."--Prové de l'editor. DNA nanotechnology: From structure to function presents an overview of various facets of DNA nanotechnology, with a particular focus on their promising applications. This book is composed of three parts. Part I, Elements of DNA Nanotechnology, provides extensive basic information on DNA nanotechnology. Part II, Static and Dynamic DNA Nanotechnology, describes the design and fabrication of static and dynamic DNA nanostructures. Recent advances in DNA origami, DNA walkers and DNA nanodevices are all covered in this part. Part III, Applications of DNA Nanotechnology, introduces a variety of applications of DNA nanotechnology, including biosensing, computation, drug delivery, etc. Together these provide a comprehensive overview of this emerging area and its broad impact on biological and medical sciences.This book is intended for post-graduates, post-doctoral researchers and research scientists who are interested in expanding their knowledge of DNA nanotechnology. It provides readers an impression of the latest developments in this exciting filed.