DNA Structure and Function , a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Special Features * Explains basic DNA Structure and function clearly and simply * Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations * Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure * Highlights key experiments and ideas within boxed sections * Illustrated with 150 diagrams and figures that convey structural and experimental concepts Content: Front Matter , Page iii Copyright , Page iv Dedication , Page v Preface , Pages xvii-xix , Richard R. Sinden Foreword , Pages xxi-xxiii , David M.J. Lilley CHAPTER 1 - Introduction to the Structure, Properties, and Reactions of DNA , Pages 1-57 , Richard R. Sinden CHAPTER 2 - DNA Bending , Pages 58-94 , Richard R. Sinden CHAPTER 3 - DNA Supercoiling , Pages 95-133 , Richard R. Sinden CHAPTER 4 - Cruciform Structures in DNA , Pages 134-178 , Richard R. Sinden CHAPTER 5 - Left-Handed Z-DNA , Pages 179-216 , Richard R. Sinden CHAPTER 6 - Triplex DNA , Pages 217-258 , Richard R. Sinden CHAPTER 7 - Miscellaneous Alternative Conformations of DNA , Pages 259-286 , Richard R. Sinden CHAPTER 8 - DNA–Protein Interactions , Pages 287-325 , Richard R. Sinden CHAPTER 9 - The Organization of DNA into Chromosomes , Pages 326-352 , Richard R. Sinden Bibliography , Pages 353-386 Author Index , Pages 387-391 Subject Index , Pages 393-398 DNA Structure and Function, a timely and comprehensive resource, is intended for any student or scientist interested in DNA structure and its biological implications. The book provides a simple yet comprehensive introduction to nearly all aspects of DNA structure. It also explains current ideas on the biological significance of classic and alternative DNA conformations. Suitable for graduate courses on DNA structure and nucleic acids, the text is also excellent supplemental reading for courses in general biochemistry, molecular biology, and genetics. Special Features * Explains basic DNA Structure and function clearly and simply * Contains up-to-date coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations * Discusses DNA-protein interactions, chromosomal organization, and biological implications of structure * Highlights key experiments and ideas within boxed sections * Illustrated with 150 diagrams and figures that convey structural and experimental concepts Provides a simple introduction to various aspects of DNA structure. This book explains ideas on the biological significance of classic and alternative DNA conformations. It explains basic DNA Structure and function, and contains coverage of cruciforms, Z-DNA, triplex DNA, and other DNA conformations. It also discusses DNA-protein interactions.
