Endocrinology of Cardiovascular Function

__Endocrinology of Cardiovascular Function__ is a fitting inauguration to the __Endocrine Update Series__. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Historically, our understanding of hormonal disturbances was restricted to the classical secretory glands and their targets. As __Endocrinology of Cardiovascular Function__ so aptly indicates, endocrinology is no longer constrained by our early physiologic understanding of glandular disorder. __Endocrinology of____Cardiovascular Function__ has set the standard of excellence for the future volumes in this series. Shlomo Melmed, M.D. Series Editor, __Endocrine Update__ Growth factors such as IGF-1 play important roles in cardiovascular cell hypertrophy and the response to acute vascular injury. From another perspective, traditional endocrine hormones, such as estrogen, have been found to participate in preventing the development of atherosclerosis in women, acting through novel mechanisms on target vascular cells. Other `endocrine' hormones, such as PTHRP and adrenomedullin, also modulate cardiovascular and renovascular dynamic states, suggesting new roles for these peptides as vasodilators. This multi-authored text is dedicated to highlighting emerging and important new information regarding the endocrinology of the cardiovascular system. Ellis R. Levin, M.D. Front Matter....Pages i-viii Front Matter....Pages 1-1 Cardiovascular Consequences of Estrogen Receptor Gene Mutation in Mice and Man....Pages 3-24 Sex Steroids and Endothelin....Pages 25-44 Effects of Sex Steroids in Vascular Injury....Pages 45-59 Front Matter....Pages 61-61 Angiotensin II, Growth Factors and the Lipoxygenase Pathway....Pages 63-77 Angiotensin II, Oxidative Stress, and Nitric Oxide....Pages 79-98 AT 1 versus AT 2 receptor....Pages 99-117 Front Matter....Pages 119-119 Physiology of Natriuretic Peptides....Pages 121-135 Front Matter....Pages 137-137 Insulin and Insulin-Like Growth Factor I (IGF-I) Effects on Ca 2+ and Nitric Oxide in Diabetes....Pages 139-158 Protein Glycation and Diabetic Vascular Disease....Pages 159-180 The Role of Protein Kinase C Activation in the Development of Diabetic Vascular Complications....Pages 181-196 Front Matter....Pages 197-197 Endothelin and Cardiovascular Function....Pages 199-222 Front Matter....Pages 223-223 Insulin-Like Growth Factor I and the Heart....Pages 225-234 Front Matter....Pages 235-235 Cardiovascular Biology of the Parathyroid Hormone-Related Proteins....Pages 237-254 Front Matter....Pages 255-255 Adrenomedullin: Vascular Hormone....Pages 257-278 Front Matter....Pages 279-279 Genetic Disorders of the Renin-Angiotensin-Aldsterone System Causing Hypertension....Pages 281-309 Mineralocorticoid Biosynthetic Pathways and Hypertension....Pages 311-325 Possible Interactions Among Fatty Acids, Other Lipids, and Aldosterone in the Hypertension of Obesity....Pages 327-337 Back Matter....Pages 339-347 Endocrinology of Cardiovascular Function is a fitting inauguration to the Endocrine Update Series. The aim of these publications is to provide the clinician with cutting edge, yet succinct, access to the latest advances in endocrinology. Historically, our understanding of hormonal disturbances was restricted to the classical secretory glands and their targets. As Endocrinology of Cardiovascular Function so aptly indicates, endocrinology is no longer constrained by our early physiologic understanding of glandular disorder. Endocrinology of Cardiovascular Function has set the standard of excellence for the future volumes in this series.
Shlomo Melmed, M.D. Series Editor, Endocrine Update
Growth factors such as IGF-1 play important roles in cardiovascular cell hypertrophy and the response to acute vascular injury. From another perspective, traditional endocrine hormones, such as estrogen, have been found to participate in preventing the development of atherosclerosis in women, acting through novel mechanisms on target vascular cells. Other 'endocrine' hormones, such as PTHRP and adrenomedullin, also modulate cardiovascular and renovascular dynamic states, suggesting new roles for these peptides as vasodilators. This multi-authored text is dedicated to highlighting emerging and important new information regarding the endocrinology of the cardiovascular system.
Ellis R. Levin, M.D.

The book contains black-and-white illustrations.

Edited By Ellis R. Levin And Jerry L. Nadler. Includes Bibliographical References And Index.