Spectroscopy in the biomedical sciences

"The intent of this book? a collection of manuscripts - is to provide general descriptions of analytical techniques which we believe to be useful to the biological scientist, and to provide examples of the utility of each technique. The contributing authors were asked to focus on examples in which their particular technique has proven particularly useful in studies of biological systems. Many commonly used analytical techniques such as NMR and ESR are not included in this work, it is preferred to focus on techniques which perhaps have not received as much coverage as in the recent literature. All of the analytical tools covered in this volume have great utility, and the scientific community can expect to see increasing usage of most if not all of these techniques."--Provided by publisher Cover 1 Title Page 2 Copyright Page 3 PREFACE 4 THE EDITOR 5 CONTRIBUTORS 6 Table of Contents 7 Chapter 1 Biomedical Fourier Transform Infrared Spectroscopy: Equipment and Experimental Considerations 8 Chapter 2 Biomedical Fourier Transform Infrared Spectroscopy: Applications to Proteins 28 Chapter 3 FT-IR Studies of Molecular Conformation in Biological Membranes 60 Chapter 4 Fourier Transform Mass Spectroscopy 94 Chapter 5 Electron Spectroscopy for Chemical Analysis: Applications in the Biomedical Sciences 114 Chapter 6 Biologically Relevant Applications of Vibrational Circular Dichroism 148 Chapter 7 Biomedical Applications of Raman Scattering 158 Chapter 8 Biological Applications of Total Internal Reflection Fluorescence 182 Chapter 9 Applications of Fluorescence Techniques to Automated Biological Analysis 194 Index 202